Cotrim and Hyperuricaemia - a phase IV clinical study of FDA data

Summary:

Hyperuricaemia is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are male, 40-49 old, have been taking the drug for 1 - 2 years also take Lasix, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperuricaemia when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Hyperuricaemia?

Hyperuricaemia (level of uric acid in the blood that is abnormally high) is found to be associated with 698 drugs and 794 conditions by eHealthMe. Check the latest studies of Hyperuricaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

8,881 people reported to have side effects when taking Cotrim.
Among them, 20 people (0.23%) have Hyperuricaemia.

Among these 20 people:

How long have people been on Cotrim when they have Hyperuricaemia? *

What is the gender of people who have Hyperuricaemia when taking Cotrim? *

female: 35 %
male: 65 %

What is the age of people who have Hyperuricaemia when taking Cotrim? *

What are other drugs people take besides Cotrim? *

What are other side effects people have besides Hyperuricaemia? *

Anaemia (lack of blood): 7 people, 35.00%
Blood Lactate Dehydrogenase Increased: 6 people, 30.00%
Thrombocytopenia (decrease of platelets in blood): 6 people, 30.00%
Blood Creatinine Increased: 6 people, 30.00%
Acute Kidney Failure: 5 people, 25.00%
Pneumonia: 5 people, 25.00%
Rashes (redness): 5 people, 25.00%
White Blood Cell Count Decreased: 4 people, 20.00%
Hypokalemia (low potassium): 4 people, 20.00%
Dehydration (dryness resulting from the removal of water): 4 people, 20.00%

What are the existing conditions these people have? *

Hiv Infection: 4 people, 20.00%
High Blood Pressure: 4 people, 20.00%
Castleman's Disease (a disease of lymph nodes and related tissues): 3 people, 15.00%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 15.00%
Multiple Myeloma (cancer of the plasma cells): 3 people, 15.00%
Diabetes: 2 people, 10.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 10.00%
Anaemia (lack of blood): 2 people, 10.00%
Asthma: 2 people, 10.00%
Bradycardia (abnormally slow heart action): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Hyperuricaemia?

- Check whether Hyperuricaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Hyperuricaemia treatments and more:

Hyperuricaemia (25,670 reports)

How severe was Hyperuricaemia and when was it recovered:

Hyperuricaemia in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Hyperuricaemia and drugs with ingredients of sulfamethoxazole; trimethoprim (426 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperuricaemia:

Hyperuricaemia (698 drugs)

Browse all the conditions that are associated with Hyperuricaemia:

Hyperuricaemia (794 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.