Cotrim and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Lasix, and have Hiv infection.

The phase IV clinical study analyzes which people have Weight increased when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Weight increased?

Weight increased is found to be associated with 2,888 drugs and 3,963 conditions by eHealthMe. Check the latest studies of Weight increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

8,881 people reported to have side effects when taking Cotrim.
Among them, 41 people (0.46%) have Weight increased.

Among these 41 people:

How long have people been on Cotrim when they have Weight increased? *

What is the gender of people who have Weight increased when taking Cotrim? *

female: 27.78 %
male: 72.22 %

What is the age of people who have Weight increased when taking Cotrim? *

What are other drugs people take besides Cotrim? *

What are other side effects people have besides Weight increased? *

Nausea (feeling of having an urge to vomit): 13 people, 31.71%
Fever: 11 people, 26.83%
General Physical Health Deterioration (weak health status): 11 people, 26.83%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 24.39%
Hyperlipidaemia (presence of excess lipids in the blood): 10 people, 24.39%
Hyperglycemia (high blood sugar): 10 people, 24.39%
Diabetes: 9 people, 21.95%
Hypokalemia (low potassium): 9 people, 21.95%
Anaemia (lack of blood): 8 people, 19.51%
Oedema Peripheral (superficial swelling): 8 people, 19.51%

What are the existing conditions these people have? *

Hiv Infection: 6 people, 14.63%
Traumatic Lung Injury: 3 people, 7.32%
High Blood Cholesterol: 3 people, 7.32%
Urine Output - Decreased: 2 people, 4.88%
Infection: 2 people, 4.88%
Diabetes: 2 people, 4.88%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 4.88%
Urinary Tract Infection: 2 people, 4.88%
Depression: 2 people, 4.88%
Aspergillosis (an infection caused by a fungus called aspergillus): 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Weight increased?

- Check whether Weight increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Weight increased treatments and more:

Weight increased (279,370 reports)

How severe was Weight increased and when was it recovered:

Weight increased in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Weight increased and drugs with ingredients of sulfamethoxazole; trimethoprim (4,398 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,888 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,963 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.