Coumadin and Svc obstruction - a phase IV clinical study of FDA data

Summary:

Svc obstruction is reported as a side effect among people who take Coumadin (warfarin sodium), especially for people who are female, 40-49 old, also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Svc obstruction when taking Coumadin. It is created by eHealthMe based on reports of 128,882 people who have side effects when taking Coumadin from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Svc obstruction?

Svc obstruction (superior vena cava obstruction (svco) is an uncommon complication of lung cancer) is found to be associated with 214 drugs and 337 conditions by eHealthMe. Check the latest studies of Svc obstruction.

On Jul, 07, 2026

128,882 people reported to have side effects when taking Coumadin.
Among them, 74 people (0.06%) have Svc obstruction.

Among these 74 people:

What is the gender of people who have Svc obstruction when taking Coumadin? *

female: 52.7 %
male: 47.3 %

What is the age of people who have Svc obstruction when taking Coumadin? *

What are other drugs people take besides Coumadin? *

What are other side effects people have besides Svc obstruction? *

Osteonecrosis Of Jaw (death of bone of jaw): 70 people, 94.59%
Thrombocytopenia (decrease of platelets in blood): 61 people, 82.43%
Pain: 57 people, 77.03%
Dyspnea (difficult or laboured breathing): 55 people, 74.32%
Osteopenia (a condition where bone mineral density is lower than normal): 53 people, 71.62%
Pleural Effusion (water on the lungs): 50 people, 67.57%
Oedema Peripheral (superficial swelling): 49 people, 66.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 48 people, 64.86%
Joint Pain: 45 people, 60.81%
Stress And Anxiety: 44 people, 59.46%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 24 people, 32.43%
Breast Cancer Metastatic: 16 people, 21.62%
High Blood Cholesterol: 7 people, 9.46%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 2.70%
Osteoporosis (bones weak and more likely to break): 2 people, 2.70%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 2.70%
High Blood Pressure: 2 people, 2.70%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 1.35%
Prostate Cancer Metastatic: 1 person, 1.35%
Nausea (feeling of having an urge to vomit): 1 person, 1.35%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and have Svc obstruction?

- Check whether Svc obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coumadin:

Coumadin (133,228 reports)

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Svc obstruction:

Svc obstruction (214 drugs)

Browse all the conditions that are associated with Svc obstruction:

Svc obstruction (337 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Coumadin) and Coumadin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.