Cr and Weight decreased - a phase IV clinical study of FDA data

Summary:

Weight decreased is reported as a side effect among people who take Cr (creatine), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Weight decreased when taking Cr. It is created by eHealthMe based on reports of 1,115 people who have side effects when taking Cr from the FDA, and is updated regularly.

What is Cr?

Cr has active ingredients of creatine. eHealthMe is studying from 1,389 Cr users. Check the latest studies of Cr.

What is Weight decreased?

Weight decreased is found to be associated with 3,384 drugs and 4,753 conditions by eHealthMe. Check the latest studies of Weight decreased.



On Aug, 01, 2026

1,115 people reported to have side effects when taking Cr.
Among them, 30 people (2.69%) have Weight decreased.

Could Cr cause Weight decreased?

Among these 30 people:

How long have people been on Cr when they have Weight decreased? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Weight decreased when taking Cr? *

  • female: 30 %
  • male: 70 %

What is the age of people who have Weight decreased when taking Cr? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.55 %
  • 20-29: 9.09 %
  • 30-39: 9.09 %
  • 40-49: 13.64 %
  • 50-59: 13.64 %
  • 60+: 50.0 %

What are other drugs people take besides Cr? *

  1. Xyrem: 9 people, 30.00%
  2. Vitamin D3: 6 people, 20.00%
  3. Norco: 5 people, 16.67%
  4. Magnesium: 5 people, 16.67%
  5. Vitamin B12: 5 people, 16.67%
  6. Epipen: 5 people, 16.67%
  7. Sandostatin: 5 people, 16.67%
  8. Coenzyme Q10: 4 people, 13.33%
  9. Morphine: 4 people, 13.33%
  10. Dilaudid: 4 people, 13.33%

What are other side effects people have besides Weight decreased? *

  1. Fatigue (feeling of tiredness): 11 people, 36.67%
  2. Diarrhea: 9 people, 30.00%
  3. Oedema Peripheral (superficial swelling): 8 people, 26.67%
  4. Urinary Tract Infection: 8 people, 26.67%
  5. Hypokalemia (low potassium): 8 people, 26.67%
  6. Dizziness: 7 people, 23.33%
  7. Joint Pain: 7 people, 23.33%
  8. Nausea And Vomiting: 7 people, 23.33%
  9. Arthropathy: 7 people, 23.33%
  10. Insomnia (sleeplessness): 6 people, 20.00%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 30.00%
  2. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 5 people, 16.67%
  3. Renal Disorder (kidney disease): 5 people, 16.67%
  4. Cardiac Failure: 4 people, 13.33%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 13.33%
  6. Stress And Anxiety: 4 people, 13.33%
  7. Rashes (redness): 3 people, 10.00%
  8. Pre-Existing Disease: 3 people, 10.00%
  9. Cardiac Failure Chronic: 3 people, 10.00%
  10. Itching: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cr and have Weight decreased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cr:

  • Cr (1,389 reports)

Weight decreased treatments and more:

How severe was Weight decreased and when was it recovered:

Expand to all the drugs that have ingredients of creatine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight decreased:

Browse all the conditions that are associated with Weight decreased:


How the study uses the data?

The study uses data from the FDA. It is based on creatine (the active ingredients of Cr) and Cr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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