Creon and Hypercalcaemia aggravated - a phase IV clinical study of FDA data

Summary:

Hypercalcaemia aggravated is reported as a side effect among people who take Creon (pancrelipase (amylase;lipase;protease)), especially for people who are male, 60+ old, also take Lantus, and have Lung neoplasm malignant.

The phase IV clinical study analyzes which people have Hypercalcaemia aggravated when taking Creon. It is created by eHealthMe based on reports of 29,220 people who have side effects when taking Creon from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Hypercalcaemia aggravated?

Hypercalcaemia aggravated (elevated calcium (ca+) level in the blood. (norma) is found to be associated with 932 drugs and 344 conditions by eHealthMe. Check the latest studies of Hypercalcaemia aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

29,220 people reported to have side effects when taking Creon.
Among them, 22 people (0.08%) have Hypercalcaemia aggravated.

Could Creon cause Hypercalcaemia aggravated?

Among these 22 people:

What is the gender of people who have Hypercalcaemia aggravated when taking Creon? *

female: 31.82 %
male: 68.18 %

What is the age of people who have Hypercalcaemia aggravated when taking Creon? *

What are other drugs people take besides Creon? *

What are other side effects people have besides Hypercalcaemia aggravated? *

Diarrhea: 6 people, 27.27%
Weight Decreased: 5 people, 22.73%
Malignant Neoplasm Progression (cancer tumour came back): 5 people, 22.73%
Peripheral Ischaemia (impaired circulation to an extremity): 4 people, 18.18%
Dehydration (dryness resulting from the removal of water): 4 people, 18.18%
Fatigue (feeling of tiredness): 4 people, 18.18%
Inflammation: 4 people, 18.18%
Abdominal Pain: 4 people, 18.18%
Keratitis Fungal (inflammation of the cornea due to fungal organism): 3 people, 13.64%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 13.64%

What are the existing conditions these people have? *

Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 18.18%
Muscle Aches (muscle pain): 2 people, 9.09%
Thyroid Cancer: 2 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.09%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 9.09%
Prostatomegaly (enlargement of the prostate): 2 people, 9.09%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 2 people, 9.09%
Blood Potassium Decreased: 2 people, 9.09%
Calcium Deficiency (lack of calcium): 2 people, 9.09%
High Blood Cholesterol: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Creon and have Hypercalcaemia aggravated?

- Check whether Hypercalcaemia aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Creon:

Creon (29,489 reports)

Hypercalcaemia aggravated treatments and more:

Hypercalcaemia aggravated (1 reports)

How severe was Hypercalcaemia aggravated and when was it recovered:

Hypercalcaemia aggravated in Creon

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Hypercalcaemia aggravated and drugs with ingredients of pancrelipase (amylase;lipase;protease)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Creon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercalcaemia aggravated:

Hypercalcaemia aggravated (932 drugs)

Browse all the conditions that are associated with Hypercalcaemia aggravated:

Hypercalcaemia aggravated (344 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Creon) and Creon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.