Crestor and Epidermal necrosis - a phase IV clinical study of FDA data

Summary:

Epidermal necrosis is reported as a side effect among people who take Crestor (rosuvastatin calcium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have High blood pressure.

The phase IV clinical study analyzes which people have Epidermal necrosis when taking Crestor. It is created by eHealthMe based on reports of 143,349 people who have side effects when taking Crestor from the FDA, and is updated regularly.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.

What is Epidermal necrosis?

Epidermal necrosis (skin condition that is usually caused by a reaction to drugs) is found to be associated with 142 drugs and 317 conditions by eHealthMe. Check the latest studies of Epidermal necrosis.

On Jul, 06, 2026

143,349 people reported to have side effects when taking Crestor.
Among them, 11 people (0.01%) have Epidermal necrosis.

Among these 11 people:

How long have people been on Crestor when they have Epidermal necrosis? *

What is the gender of people who have Epidermal necrosis when taking Crestor? *

female: 50 %
male: 50 %

What is the age of people who have Epidermal necrosis when taking Crestor? *

What are other drugs people take besides Crestor? *

Voltaren: 3 people, 27.27%
Plavix: 3 people, 27.27%
Lasix: 3 people, 27.27%
Calciparine: 2 people, 18.18%
Lorazepam: 2 people, 18.18%
Esomeprazole Magnesium: 2 people, 18.18%
Folic Acid: 2 people, 18.18%
Halcion: 2 people, 18.18%
Ibuprofen: 2 people, 18.18%
Xanax: 2 people, 18.18%

What are other side effects people have besides Epidermal necrosis? *

Rashes (redness): 6 people, 54.55%
Fever: 5 people, 45.45%
Mouth Ulcers: 4 people, 36.36%
Erythema Multiforme (a type of hypersensitivity reaction): 4 people, 36.36%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 4 people, 36.36%
Eye Discharge: 3 people, 27.27%
Lymphocytic Infiltration (lymphocyte deposition): 3 people, 27.27%
Generalised Erythema (redness of the skin all over the body): 3 people, 27.27%
Gamma-Glutamyltransferase Increased: 3 people, 27.27%
Scab (a hard coating on the skin formed during the wound healing): 3 people, 27.27%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 36.36%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 27.27%
Pemphigoid (tense blisters on the skin): 2 people, 18.18%
Pain: 2 people, 18.18%
Joint Pain: 2 people, 18.18%
Insomnia (sleeplessness): 2 people, 18.18%
Erysipelas (bacterial skin infection): 2 people, 18.18%
Dyslipidaemia (abnormal amount of lipids): 2 people, 18.18%
Depression: 2 people, 18.18%
Cardiomyopathy (weakening of the heart muscle): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Crestor and have Epidermal necrosis?

- Check whether Epidermal necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Crestor:

Crestor (149,761 reports)

Browse all side effects of Crestor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epidermal necrosis:

Epidermal necrosis (142 drugs)

Browse all the conditions that are associated with Epidermal necrosis:

Epidermal necrosis (317 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rosuvastatin calcium (the active ingredients of Crestor) and Crestor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.