Crestor and Muscle enzyme increased - a phase IV clinical study of FDA data

Summary:

Muscle enzyme increased is reported as a side effect among people who take Crestor (rosuvastatin calcium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Muscle enzyme increased when taking Crestor. It is created by eHealthMe based on reports of 143,349 people who have side effects when taking Crestor from the FDA, and is updated regularly.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,763 Crestor users. Check the latest studies of Crestor.

What is Muscle enzyme increased?

Muscle enzyme increased is found to be associated with 58 drugs and 177 conditions by eHealthMe. Check the latest studies of Muscle enzyme increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

143,349 people reported to have side effects when taking Crestor.
Among them, 36 people (0.03%) have Muscle enzyme increased.

Could Crestor cause Muscle enzyme increased?

Among these 36 people:

How long have people been on Crestor when they have Muscle enzyme increased? *

What is the gender of people who have Muscle enzyme increased when taking Crestor? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Muscle enzyme increased when taking Crestor? *

What are other drugs people take besides Crestor? *

What are other side effects people have besides Muscle enzyme increased? *

Muscle Aches (muscle pain): 18 people, 50.00%
Weakness: 11 people, 30.56%
Weight Decreased: 7 people, 19.44%
Blood Creatine Phosphokinase Increased: 6 people, 16.67%
Muscle Spasms (muscle contraction): 6 people, 16.67%
Headache (pain in head): 5 people, 13.89%
Pain In Extremity: 5 people, 13.89%
Hepatic Enzyme Increased: 4 people, 11.11%
Blood Lactate Dehydrogenase Increased: 4 people, 11.11%
Joint Pain: 4 people, 11.11%

What are the existing conditions these people have? *

Blood Pressure Abnormal: 3 people, 8.33%
Nausea (feeling of having an urge to vomit): 3 people, 8.33%
High Blood Pressure: 3 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.33%
Asthma: 2 people, 5.56%
Muscle Spasms (muscle contraction): 2 people, 5.56%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 5.56%
Diabetes: 2 people, 5.56%
Vitamin B12 Deficiency: 1 person, 2.78%
Folate Deficiency (lack of folic acid): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Crestor and have Muscle enzyme increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Crestor:

Crestor (149,763 reports)

Browse all side effects of Crestor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle enzyme increased:

Muscle enzyme increased (58 drugs)

Browse all the conditions that are associated with Muscle enzyme increased:

Muscle enzyme increased (177 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rosuvastatin calcium (the active ingredients of Crestor) and Crestor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.