Cyanocobalamin and Dementia - a phase IV clinical study of FDA data


We study 11,147 people who have side effects when taking Cyanocobalamin. Dementia is found, especially among people who are male, 60+ old, have been taking the drug for 2 - 5 years, also take Aspirin and have Parkinson's disease.

The phase IV clinical study analyzes which people take Cyanocobalamin and have Dementia. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 18, 2023

11,147 people reported to have side effects when taking Cyanocobalamin.
Among them, 20 people (0.18%) have Dementia.

What is Cyanocobalamin?

Cyanocobalamin has active ingredients of cyanocobalamin. It is used in vitamin b12 deficiency. Currently, eHealthMe is studying from 11,327 Cyanocobalamin users.

What is Dementia?

Dementia (madness) is found to be associated with 2,447 drugs and 1,749 conditions by eHealthMe. Currently, we are studying 41,468 people who have Dementia.

Number of Cyanocobalamin and Dementia reports submitted per year:

Could Cyanocobalamin cause Dementia?

Time on Cyanocobalamin when people have Dementia *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Dementia when taking Cyanocobalamin *:

  • female: 36.84 %
  • male: 63.16 %

Age of people who have Dementia when taking Cyanocobalamin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Cyanocobalamin *:

  1. Aspirin: 8 people, 40.00%
  2. Acetaminophen: 3 people, 15.00%
  3. Folic Acid: 3 people, 15.00%
  4. Lipitor: 3 people, 15.00%
  5. Nuplazid: 3 people, 15.00%
  6. Brilinta: 3 people, 15.00%
  7. Fosamax: 3 people, 15.00%
  8. Vitamin D3: 3 people, 15.00%
  9. Allopurinol: 3 people, 15.00%
  10. Doxil: 2 people, 10.00%

Common side effects people have besides Dementia *:

  1. Depressed Level Of Consciousness: 3 people, 15.00%
  2. Depression: 3 people, 15.00%
  3. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 3 people, 15.00%
  4. Confusional State: 3 people, 15.00%
  5. Haematocrit Decreased: 3 people, 15.00%
  6. Haemoglobin Decreased: 3 people, 15.00%
  7. Insomnia (sleeplessness): 3 people, 15.00%
  8. Hallucinations (sensations that appear real but are created by your mind): 3 people, 15.00%
  9. Fatigue (feeling of tiredness): 3 people, 15.00%
  10. Fall: 3 people, 15.00%

Common conditions people have *:

  1. Parkinson's Disease: 4 people, 20.00%
  2. Pain: 2 people, 10.00%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.00%
  4. Swallowing Difficulty: 1 person, 5.00%
  5. Hallucinations (sensations that appear real but are created by your mind): 1 person, 5.00%
  6. Agitation (state of anxiety or nervous excitement): 1 person, 5.00%
  7. Bone Pain: 1 person, 5.00%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.00%
  9. Depression: 1 person, 5.00%
  10. Folate Deficiency (lack of folic acid): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cyanocobalamin and have Dementia?

Check whether Dementia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Cyanocobalamin side effects by duration, gender and age:

Dementia treatments and more:

Common drugs associated with Dementia:

All the drugs that are associated with Dementia:

Common conditions associated with Dementia:

All the conditions that are associated with Dementia:

How the study uses the data?

The study uses data from the FDA. It is based on cyanocobalamin (the active ingredients of Cyanocobalamin) and Cyanocobalamin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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