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Cyclophosphamide and Aortic thrombosis - a phase IV clinical study of FDA data

Summary:

Aortic thrombosis is reported as a side effect among people who take Cyclophosphamide (cyclophosphamide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Rituxan, and have Non-hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Aortic thrombosis when taking Cyclophosphamide. It is created by eHealthMe based on reports of 185,094 people who have side effects when taking Cyclophosphamide from the FDA, and is updated regularly.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

What is Aortic thrombosis?

Aortic thrombosis (formation of a blood clot inside aorta) is found to be associated with 170 drugs and 316 conditions by eHealthMe. Check the latest studies of Aortic thrombosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

185,094 people reported to have side effects when taking Cyclophosphamide.
Among them, 23 people (0.01%) have Aortic thrombosis.

Could Cyclophosphamide cause Aortic thrombosis?

Among these 23 people:

How long have people been on Cyclophosphamide when they have Aortic thrombosis? *

  • < 1 month: 30.77 %
  • 1 - 6 months: 69.23 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Aortic thrombosis when taking Cyclophosphamide? *

  • female: 68.18 %
  • male: 31.82 %

What is the age of people who have Aortic thrombosis when taking Cyclophosphamide? *

  • 0-1: 15 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 5 %
  • 60+: 70 %

What are other drugs people take besides Cyclophosphamide? *

  1. Rituxan: 6 people, 26.09%
  2. Oncovin: 5 people, 21.74%
  3. Fluconazole: 3 people, 13.04%
  4. Doxorubicin Hydrochloride: 3 people, 13.04%
  5. Narcan: 2 people, 8.70%
  6. Claritin: 2 people, 8.70%
  7. Compazine: 2 people, 8.70%
  8. Decadron: 2 people, 8.70%
  9. Diflucan: 2 people, 8.70%
  10. Dilaudid: 2 people, 8.70%

What are other side effects people have besides Aortic thrombosis? *

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 21.74%
  2. Foetal Growth Restriction (poor growth of a baby while in the mother's womb during pregnancy): 4 people, 17.39%
  3. Febrile Neutropenia (fever with reduced white blood cells): 4 people, 17.39%
  4. Pleural Effusion (water on the lungs): 3 people, 13.04%
  5. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 3 people, 13.04%
  6. Hypotension (abnormally low blood pressure): 3 people, 13.04%
  7. Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 13.04%
  8. Splenic Infarction (tissue damage of spleen): 3 people, 13.04%
  9. Bradycardia (abnormally slow heart action): 3 people, 13.04%
  10. Fever: 2 people, 8.70%

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 8 people, 34.78%
  2. Breast Cancer: 7 people, 30.43%
  3. Pain: 2 people, 8.70%
  4. Acute Myocardial Infarction (acute heart attack): 2 people, 8.70%
  5. Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 4.35%
  6. Myelodysplastic Syndrome Unclassifiable (there are too few of one type of blood cell in the blood. the number of blasts in the bone marrow and blood is normal): 1 person, 4.35%
  7. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 4.35%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 4.35%
  9. Birth Control: 1 person, 4.35%
  10. Amyloidosis (a tumour within which amyloid is produced): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Cyclophosphamide and have Aortic thrombosis?

- Check whether Aortic thrombosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cyclophosphamide:

Aortic thrombosis treatments and more:

How severe was Aortic thrombosis and when was it recovered:

Expand to all the drugs that have ingredients of cyclophosphamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic thrombosis:

Browse all the conditions that are associated with Aortic thrombosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on cyclophosphamide (the active ingredients of Cyclophosphamide) and Cyclophosphamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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