Danazol and Atrial fibrillation/flutter - a phase IV clinical study of FDA data

Summary:

Atrial fibrillation/flutter is reported as a side effect among people who take Danazol (danazol), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Soliris, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Atrial fibrillation/flutter when taking Danazol. It is created by eHealthMe based on reports of 3,687 people who have side effects when taking Danazol from the FDA, and is updated regularly.

What is Danazol?

Danazol has active ingredients of danazol. It is often used in hereditary angioedema. eHealthMe is studying from 3,716 Danazol users. Check the latest studies of Danazol.

What is Atrial fibrillation/flutter?

Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles) is found to be associated with 2,362 drugs and 3,844 conditions by eHealthMe. Check the latest studies of Atrial fibrillation/flutter.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

3,687 people reported to have side effects when taking Danazol.
Among them, 37 people (1.0%) have Atrial fibrillation/flutter.

Could Danazol cause Atrial fibrillation/flutter?

Among these 37 people:

How long have people been on Danazol when they have Atrial fibrillation/flutter? *

What is the gender of people who have Atrial fibrillation/flutter when taking Danazol? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Atrial fibrillation/flutter when taking Danazol? *

What are other drugs people take besides Danazol? *

What are other side effects people have besides Atrial fibrillation/flutter? *

Thrombocytopenia (decrease of platelets in blood): 15 people, 40.54%
Haemoglobin Decreased: 10 people, 27.03%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 8 people, 21.62%
Dyspnea (difficult or laboured breathing): 8 people, 21.62%
Weakness: 8 people, 21.62%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 18.92%
Fatigue (feeling of tiredness): 7 people, 18.92%
Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 18.92%
Drug Ineffective: 7 people, 18.92%
Gastritis (inflammation of stomach): 6 people, 16.22%

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 8 people, 21.62%
Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 16.22%
Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 5 people, 13.51%
Nausea (feeling of having an urge to vomit): 3 people, 8.11%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 8.11%
Thrombocytopenia (decrease of platelets in blood): 2 people, 5.41%
Insomnia (sleeplessness): 2 people, 5.41%
Weight Decreased: 2 people, 5.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.41%
Depression: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Danazol and have Atrial fibrillation/flutter?

- Check whether Atrial fibrillation/flutter is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Danazol:

Danazol (3,716 reports)

Browse all side effects of Danazol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (2,362 drugs)

Browse all the conditions that are associated with Atrial fibrillation/flutter:

Atrial fibrillation/flutter (3,844 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on danazol (the active ingredients of Danazol) and Danazol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.