Daptomycin and Drug level increased - a phase IV clinical study of FDA data

Summary:

Drug level increased is reported as a side effect among people who take Daptomycin (daptomycin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Letermovir, and have Staphylococcal infection.

The phase IV clinical study analyzes which people have Drug level increased when taking Daptomycin. It is created by eHealthMe based on reports of 7,865 people who have side effects when taking Daptomycin from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Drug level increased?

Drug level increased is found to be associated with 874 drugs and 1,136 conditions by eHealthMe. Check the latest studies of Drug level increased.

On Jul, 09, 2026

7,865 people reported to have side effects when taking Daptomycin.
Among them, 43 people (0.55%) have Drug level increased.

Could Daptomycin cause Drug level increased?

Among these 43 people:

How long have people been on Daptomycin when they have Drug level increased? *

What is the gender of people who have Drug level increased when taking Daptomycin? *

female: 27.5 %
male: 72.5 %

What is the age of people who have Drug level increased when taking Daptomycin? *

What are other drugs people take besides Daptomycin? *

Letermovir: 22 people, 51.16%
Piperacillin And Tazobactam: 17 people, 39.53%
Methylprednisolone: 7 people, 16.28%
Atovaquone: 7 people, 16.28%
Cyclosporine: 7 people, 16.28%
Meropenem: 7 people, 16.28%
Acyclovir: 7 people, 16.28%
Mycophenolic Acid: 5 people, 11.63%
Vancomycin: 5 people, 11.63%
Mycophenolate Mofetil: 3 people, 6.98%

What are other side effects people have besides Drug level increased? *

Septic Shock (shock due to blood infection): 26 people, 60.47%
Hepatic Failure (liver failure): 22 people, 51.16%
Altered State Of Consciousness (altered state of mind): 20 people, 46.51%
Hallucination, Visual (seeing things that aren't there): 5 people, 11.63%
Drug Level Decreased: 5 people, 11.63%
Lactic Acidosis (low ph in body tissues): 4 people, 9.30%
Drug Level Below Therapeutic: 2 people, 4.65%
Depressed Level Of Consciousness: 2 people, 4.65%
Headache (pain in head): 1 person, 2.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.33%

What are the existing conditions these people have? *

Staphylococcal Infection (an infection with staphylococcus bacteria): 10 people, 23.26%
Immunodeficiency Disorders: 5 people, 11.63%
Abdominal Discomfort: 5 people, 11.63%
Arthritis Infective (purulent invasion of a joint by an infectious agent which produces arthritis): 4 people, 9.30%
Wound Infection Staphylococcal: 3 people, 6.98%
Endocarditis (inflammation in heart muscle): 3 people, 6.98%
Enterococcal Infection: 2 people, 4.65%
Septic Shock (shock due to blood infection): 1 person, 2.33%
Osteomyelitis (infection of bone): 1 person, 2.33%
Klebsiella Infection: 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Daptomycin and have Drug level increased?

- Check whether Drug level increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Daptomycin:

Daptomycin (7,879 reports)

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug level increased:

Drug level increased (874 drugs)

Browse all the conditions that are associated with Drug level increased:

Drug level increased (1,136 conditions)

Related publications that referenced our studies

Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .
Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on daptomycin (the active ingredients of Daptomycin) and Daptomycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.