Daraprim and Weakness - a phase IV clinical study of FDA data
Summary:
Weakness is reported as a side effect among people who take Daraprim (pyrimethamine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Sulfadiazine, and have Toxoplasmosis.
The phase IV clinical study analyzes which people have Weakness when taking Daraprim. It is created by eHealthMe based on reports of 783 people who have side effects when taking Daraprim from the FDA, and is updated regularly.
What is Daraprim?
Daraprim has active ingredients of pyrimethamine. eHealthMe is studying from 788 Daraprim users. Check the latest studies of Daraprim.
What is Weakness?
Weakness is found to be associated with 3,643 drugs and 6,610 conditions by eHealthMe. Check the latest studies of Weakness.
783 people reported to have side effects when taking Daraprim.
Among them, 33 people (4.21%) have Weakness.

Among these 33 people:
How long have people been on Daraprim when they have Weakness? *
- < 1 month: 92.31 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 7.69 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Weakness when taking Daraprim? *
- female: 66.67 %
- male: 33.33 %
What is the age of people who have Weakness when taking Daraprim? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 3.45 %
- 20-29: 0.0 %
- 30-39: 27.59 %
- 40-49: 27.59 %
- 50-59: 20.69 %
- 60+: 20.69 %
What are other drugs people take besides Daraprim? *
- Sulfadiazine: 12 people, 36.36%
- Leucovorin Calcium: 8 people, 24.24%
- Famotidine: 6 people, 18.18%
- Keppra: 6 people, 18.18%
- Dexamethasone: 5 people, 15.15%
- Atripla: 3 people, 9.09%
- Plavix: 3 people, 9.09%
- Viread: 3 people, 9.09%
- Vitamin D3: 3 people, 9.09%
- Pantoprazole: 3 people, 9.09%
What are other side effects people have besides Weakness? *
- Fatigue (feeling of tiredness): 11 people, 33.33%
- Malaise (a feeling of general discomfort or uneasiness): 8 people, 24.24%
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 7 people, 21.21%
- Fall: 6 people, 18.18%
- Heart Palpitations (feelings or sensations that your heart is pounding or racing): 5 people, 15.15%
- Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 15.15%
- Headache (pain in head): 5 people, 15.15%
- Mouth Ulcers: 5 people, 15.15%
- Pain: 4 people, 12.12%
- Memory Loss: 4 people, 12.12%
What are the existing conditions these people have? *
- Toxoplasmosis (a parasitic disease caused by the protozoan toxoplasma gondii): 13 people, 39.39%
- Hiv Infection: 6 people, 18.18%
- Eye Infection Toxoplasmal (a germ called toxoplasma can cause infection within the eye): 5 people, 15.15%
- Gastrointestinal Disorder (functional problems of gastrointestinal tract): 5 people, 15.15%
- Cerebral Toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii): 2 people, 6.06%
- Hiv Test Positive: 2 people, 6.06%
- Gout (uric acid crystals building up in the body): 1 person, 3.03%
- Asthma: 1 person, 3.03%
- Back Pain: 1 person, 3.03%
- Bacterial Infection: 1 person, 3.03%
* Approximation only. Some reports may have incomplete information.
Do you take Daraprim and have Weakness?
- Check whether Weakness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Daraprim:
- Daraprim (788 reports)
Weakness treatments and more:
- Weakness (586,876 reports)
How severe was Weakness and when was it recovered:
Expand to all the drugs that have ingredients of pyrimethamine:
- Weakness and drugs with ingredients of pyrimethamine (123 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Daraprim:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Weakness:
- Weakness (3,643 drugs)
Browse all the conditions that are associated with Weakness:
- Weakness (6,610 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on pyrimethamine (the active ingredients of Daraprim) and Daraprim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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