Darvon and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Darvon (propoxyphene hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Vioxx, and have Macular degeneration.

The phase IV clinical study analyzes which people have Stroke when taking Darvon. It is created by eHealthMe based on reports of 2,707 people who have side effects when taking Darvon from the FDA, and is updated regularly.

What is Darvon?

Darvon has active ingredients of propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 2,762 Darvon users. Check the latest studies of Darvon.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,310 drugs and 3,035 conditions by eHealthMe. Check the latest studies of Stroke.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

2,707 people reported to have side effects when taking Darvon.
Among them, 37 people (1.37%) have Stroke.

Among these 37 people:

How long have people been on Darvon when they have Stroke? *

What is the gender of people who have Stroke when taking Darvon? *

female: 70.27 %
male: 29.73 %

What is the age of people who have Stroke when taking Darvon? *

What are other drugs people take besides Darvon? *

What are other side effects people have besides Stroke? *

Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 10 people, 27.03%
High Blood Pressure: 8 people, 21.62%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 16.22%
Acute Myocardial Infarction (acute heart attack): 6 people, 16.22%
Weakness: 6 people, 16.22%
Carotid Artery Stenosis (narrowing of carotid artery): 6 people, 16.22%
Hypotension (abnormally low blood pressure): 6 people, 16.22%
Depression: 6 people, 16.22%
Thrombosis (formation of a blood clot inside a blood vessel): 5 people, 13.51%
Hyperglycemia (high blood sugar): 5 people, 13.51%

What are the existing conditions these people have? *

Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 5 people, 13.51%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 10.81%
Depression: 3 people, 8.11%
Inflammation: 2 people, 5.41%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 2.70%
Joint Pain: 1 person, 2.70%
High Blood Pressure: 1 person, 2.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.70%
Back Pain: 1 person, 2.70%
Affective Disorder (mental disorder): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Darvon and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Darvon:

Darvon (2,762 reports)

Stroke treatments and more:

Stroke (334,635 reports)

Browse all side effects of Darvon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,310 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,035 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on propoxyphene hydrochloride (the active ingredients of Darvon) and Darvon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.