Darvon and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Darvon (propoxyphene hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Vicodin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Weakness when taking Darvon. It is created by eHealthMe based on reports of 2,707 people who have side effects when taking Darvon from the FDA, and is updated regularly.

What is Darvon?

Darvon has active ingredients of propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 2,762 Darvon users. Check the latest studies of Darvon.

What is Weakness?

Weakness is found to be associated with 3,640 drugs and 6,615 conditions by eHealthMe. Check the latest studies of Weakness.



On Aug, 01, 2026

2,707 people reported to have side effects when taking Darvon.
Among them, 44 people (1.63%) have Weakness.

Could Darvon cause Weakness?

Among these 44 people:

How long have people been on Darvon when they have Weakness? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Weakness when taking Darvon? *

  • female: 73.81 %
  • male: 26.19 %

What is the age of people who have Weakness when taking Darvon? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.94 %
  • 30-39: 0.0 %
  • 40-49: 5.88 %
  • 50-59: 20.59 %
  • 60+: 70.59 %

What are other drugs people take besides Darvon? *

  1. Vicodin: 9 people, 20.45%
  2. Prednisone: 8 people, 18.18%
  3. Celebrex: 7 people, 15.91%
  4. Zocor: 7 people, 15.91%
  5. Premarin: 7 people, 15.91%
  6. Protonix: 7 people, 15.91%
  7. Zometa: 7 people, 15.91%
  8. Lasix: 7 people, 15.91%
  9. Furosemide: 7 people, 15.91%
  10. Aspirin: 6 people, 13.64%

What are other side effects people have besides Weakness? *

  1. Fever: 13 people, 29.55%
  2. Dizziness: 10 people, 22.73%
  3. Pain In Extremity: 10 people, 22.73%
  4. Joint Pain: 10 people, 22.73%
  5. Pneumonia: 9 people, 20.45%
  6. Hypotension (abnormally low blood pressure): 8 people, 18.18%
  7. Diarrhea: 8 people, 18.18%
  8. Dehydration (dryness resulting from the removal of water): 8 people, 18.18%
  9. Hypoaesthesia (reduced sense of touch or sensation): 7 people, 15.91%
  10. Fatigue (feeling of tiredness): 7 people, 15.91%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 13.64%
  2. Multiple Myeloma (cancer of the plasma cells): 4 people, 9.09%
  3. Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 3 people, 6.82%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 6.82%
  5. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 4.55%
  6. Depression: 2 people, 4.55%
  7. Osteolysis (dissolution of bone): 1 person, 2.27%
  8. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 2.27%
  9. Back Pain: 1 person, 2.27%
  10. Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Darvon and have Weakness?

- Check whether Weakness is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Darvon:

Weakness treatments and more:

How severe was Weakness and when was it recovered:

Expand to all the drugs that have ingredients of propoxyphene hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Darvon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Browse all the conditions that are associated with Weakness:


How the study uses the data?

The study uses data from the FDA. It is based on propoxyphene hydrochloride (the active ingredients of Darvon) and Darvon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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