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Demadex and Osteoporosis - a phase IV clinical study of FDA data

Summary:

Osteoporosis is reported as a side effect among people who take Demadex (torsemide), especially for people who are female, 60+ old, also take Fosamax, and have Metastatic neoplasm.

The phase IV clinical study analyzes which people have Osteoporosis when taking Demadex. It is created by eHealthMe based on reports of 5,316 people who have side effects when taking Demadex from the FDA, and is updated regularly.

What is Demadex?

Demadex has active ingredients of torsemide. It is often used in heart failure. eHealthMe is studying from 5,358 Demadex users. Check the latest studies of Demadex.

What is Osteoporosis?

Osteoporosis (bones weak and more likely to break) is found to be associated with 1,806 drugs and 1,905 conditions by eHealthMe. Check the latest studies of Osteoporosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 26, 2026

5,316 people reported to have side effects when taking Demadex.
Among them, 44 people (0.83%) have Osteoporosis.

Could Demadex cause Osteoporosis?

Among these 44 people:

What is the gender of people who have Osteoporosis when taking Demadex? *

  • female: 81.4 %
  • male: 18.6 %

What is the age of people who have Osteoporosis when taking Demadex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 8.7 %
  • 30-39: 0.0 %
  • 40-49: 21.74 %
  • 50-59: 17.39 %
  • 60+: 52.17 %

What are other drugs people take besides Demadex? *

  1. Fosamax: 29 people, 65.91%
  2. Lasix: 23 people, 52.27%
  3. Zyrtec: 22 people, 50.00%
  4. Restoril: 22 people, 50.00%
  5. Lexapro: 20 people, 45.45%
  6. Norco: 19 people, 43.18%
  7. Zantac: 19 people, 43.18%
  8. Zometa: 19 people, 43.18%
  9. Metolazone: 18 people, 40.91%
  10. Meloxicam: 18 people, 40.91%

What are other side effects people have besides Osteoporosis? *

  1. Stress And Anxiety: 29 people, 65.91%
  2. Depression: 29 people, 65.91%
  3. Fall: 27 people, 61.36%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 26 people, 59.09%
  5. Pain: 26 people, 59.09%
  6. Oedema Peripheral (superficial swelling): 25 people, 56.82%
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 24 people, 54.55%
  8. Cardiac Failure Congestive: 24 people, 54.55%
  9. Dyspnea Exertional: 23 people, 52.27%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 23 people, 52.27%

What are the existing conditions these people have? *

  1. Breast Cancer Metastatic: 17 people, 38.64%
  2. Metastatic Neoplasm (spreadable cancer tumour): 17 people, 38.64%
  3. Hypersensitivity: 12 people, 27.27%
  4. Diabetes: 12 people, 27.27%
  5. Pain: 6 people, 13.64%
  6. Hiv Infection: 4 people, 9.09%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.09%
  8. High Blood Pressure: 3 people, 6.82%
  9. High Blood Cholesterol: 2 people, 4.55%
  10. Type 2 Diabetes: 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Demadex and have Osteoporosis?

- Check whether Osteoporosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Demadex:

Osteoporosis treatments and more:

How severe was Osteoporosis and when was it recovered:

Expand to all the drugs that have ingredients of torsemide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Demadex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoporosis:

Browse all the conditions that are associated with Osteoporosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on torsemide (the active ingredients of Demadex) and Demadex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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