Depo-estradiol and Memory loss - a phase IV clinical study of FDA data

Summary:

Memory loss is reported as a side effect among people who take Depo-estradiol (estradiol cypionate), especially for people who are female, 60+ old, also take Neurontin, and have Affective disorder.

The phase IV clinical study analyzes which people have Memory loss when taking Depo-estradiol. It is created by eHealthMe based on reports of 693 people who have side effects when taking Depo-estradiol from the FDA, and is updated regularly.

What is Depo-estradiol?

Depo-estradiol has active ingredients of estradiol cypionate. It is often used in birth control. eHealthMe is studying from 724 Depo-estradiol users. Check the latest studies of Depo-estradiol.

What is Memory loss?

Memory loss is found to be associated with 2,726 drugs and 4,378 conditions by eHealthMe. Check the latest studies of Memory loss.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

693 people reported to have side effects when taking Depo-estradiol.
Among them, 27 people (3.9%) have Memory loss.

Could Depo-estradiol cause Memory loss?

Among these 27 people:

What is the gender of people who have Memory loss when taking Depo-estradiol? *

  • female: 72 %
  • male: 28 %

What is the age of people who have Memory loss when taking Depo-estradiol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4 %
  • 40-49: 20 %
  • 50-59: 28 %
  • 60+: 48 %

What are other drugs people take besides Depo-estradiol? *

  1. Neurontin: 7 people, 25.93%
  2. Prevacid: 6 people, 22.22%
  3. Zanaflex: 6 people, 22.22%
  4. Vioxx: 6 people, 22.22%
  5. Lipitor: 5 people, 18.52%
  6. Cardizem: 5 people, 18.52%
  7. Serzone: 5 people, 18.52%
  8. Fiorinal: 5 people, 18.52%
  9. Vicodin: 5 people, 18.52%
  10. Elavil: 5 people, 18.52%

What are other side effects people have besides Memory loss? *

  1. Malaise (a feeling of general discomfort or uneasiness): 9 people, 33.33%
  2. Dyspnea (difficult or laboured breathing): 9 people, 33.33%
  3. Headache (pain in head): 8 people, 29.63%
  4. Pain: 7 people, 25.93%
  5. Drug Ineffective: 6 people, 22.22%
  6. Anaemia (lack of blood): 6 people, 22.22%
  7. High Blood Pressure: 6 people, 22.22%
  8. Fever: 6 people, 22.22%
  9. Mitral Valve Incompetence (inefficient heart valve): 5 people, 18.52%
  10. Migraine (headache): 5 people, 18.52%

What are the existing conditions these people have? *

  1. Hair Disorder: 3 people, 11.11%
  2. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 11.11%
  3. Affective Disorder (mental disorder): 3 people, 11.11%
  4. Weakness: 1 person, 3.70%
  5. Skin Disorder (skin disease): 1 person, 3.70%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.70%
  7. Pain: 1 person, 3.70%
  8. Neuralgia (pain in one or more nerves): 1 person, 3.70%
  9. Nerve Injury: 1 person, 3.70%
  10. Hepatitis C: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Depo-estradiol and have Memory loss?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depo-estradiol:

Memory loss treatments and more:

How severe was Memory loss and when was it recovered:

Expand to all the drugs that have ingredients of estradiol cypionate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Depo-estradiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Memory loss:

Browse all the conditions that are associated with Memory loss:


How the study uses the data?

The study uses data from the FDA. It is based on estradiol cypionate (the active ingredients of Depo-estradiol) and Depo-estradiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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