Desyrel and Gamma-glutamyltransferase increased - a phase IV clinical study of FDA data

Summary:

Gamma-glutamyltransferase increased is reported as a side effect among people who take Desyrel (trazodone hydrochloride), especially for people who are female, 50-59 old, also take Lexapro, and have Menopause.

The phase IV clinical study analyzes which people have Gamma-glutamyltransferase increased when taking Desyrel. It is created by eHealthMe based on reports of 6,042 people who have side effects when taking Desyrel from the FDA, and is updated regularly.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Gamma-glutamyltransferase increased?

Gamma-glutamyltransferase increased is found to be associated with 1,345 drugs and 2,167 conditions by eHealthMe. Check the latest studies of Gamma-glutamyltransferase increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

6,042 people reported to have side effects when taking Desyrel.
Among them, 18 people (0.3%) have Gamma-glutamyltransferase increased.

Could Desyrel cause Gamma-glutamyltransferase increased?

Among these 18 people:

What is the gender of people who have Gamma-glutamyltransferase increased when taking Desyrel? *

female: 72.22 %
male: 27.78 %

What is the age of people who have Gamma-glutamyltransferase increased when taking Desyrel? *

What are other drugs people take besides Desyrel? *

What are other side effects people have besides Gamma-glutamyltransferase increased? *

Aspartate Aminotransferase Increased: 13 people, 72.22%
Alanine Aminotransferase Increased: 13 people, 72.22%
Rashes (redness): 11 people, 61.11%
Blood Alkaline Phosphatase Increased: 10 people, 55.56%
Nausea And Vomiting: 8 people, 44.44%
Fall: 8 people, 44.44%
High Blood Pressure: 7 people, 38.89%
High Blood Cholesterol: 7 people, 38.89%
Muscle Spasms (muscle contraction): 7 people, 38.89%
Scar: 7 people, 38.89%

What are the existing conditions these people have? *

Menopause (end of monthly cycles in women): 6 people, 33.33%
White Blood Cell Count Decreased: 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 1 person, 5.56%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 5.56%
Diabetes: 1 person, 5.56%
Drowsiness: 1 person, 5.56%
Dyslipidaemia (abnormal amount of lipids): 1 person, 5.56%
Fungaemia (fungi circulate in the blood): 1 person, 5.56%
Interstitial Lung Disease: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Desyrel and have Gamma-glutamyltransferase increased?

- Check whether Gamma-glutamyltransferase increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Desyrel:

Desyrel (6,595 reports)

Browse all side effects of Desyrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gamma-glutamyltransferase increased:

Gamma-glutamyltransferase increased (1,345 drugs)

Browse all the conditions that are associated with Gamma-glutamyltransferase increased:

Gamma-glutamyltransferase increased (2,167 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trazodone hydrochloride (the active ingredients of Desyrel) and Desyrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.