Dexilant and Bipolar disorder - a phase IV clinical study of FDA data

Summary:

Bipolar disorder is reported as a side effect among people who take Dexilant (dexlansoprazole), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Nexium, and have Pain.

The phase IV clinical study analyzes which people have Bipolar disorder when taking Dexilant. It is created by eHealthMe based on reports of 56,153 people who have side effects when taking Dexilant from the FDA, and is updated regularly.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

What is Bipolar disorder?

Bipolar disorder (mood disorder) is found to be associated with 910 drugs and 1,231 conditions by eHealthMe. Check the latest studies of Bipolar disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

56,153 people reported to have side effects when taking Dexilant.
Among them, 38 people (0.07%) have Bipolar disorder.

Among these 38 people:

How long have people been on Dexilant when they have Bipolar disorder? *

What is the gender of people who have Bipolar disorder when taking Dexilant? *

female: 86.11 %
male: 13.89 %

What is the age of people who have Bipolar disorder when taking Dexilant? *

What are other drugs people take besides Dexilant? *

What are other side effects people have besides Bipolar disorder? *

Stress And Anxiety: 16 people, 42.11%
Depression: 15 people, 39.47%
Chronic Kidney Disease: 13 people, 34.21%
Acute Kidney Failure: 13 people, 34.21%
High Blood Pressure: 9 people, 23.68%
Suicidal Ideation: 6 people, 15.79%
Weight Decreased: 6 people, 15.79%
Renal Injury (kidney injury): 6 people, 15.79%
Memory Loss: 5 people, 13.16%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 13.16%

What are the existing conditions these people have? *

Pain: 12 people, 31.58%
Depression: 11 people, 28.95%
Stress And Anxiety: 10 people, 26.32%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 23.68%
Muscle Spasms (muscle contraction): 8 people, 21.05%
Blood Pressure Abnormal: 6 people, 15.79%
Dyspnea (difficult or laboured breathing): 6 people, 15.79%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 15.79%
Hypersensitivity: 5 people, 13.16%
Inflammatory Bowel Disease: 5 people, 13.16%

* Approximation only. Some reports may have incomplete information.

Do you take Dexilant and have Bipolar disorder?

- Check whether Bipolar disorder is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dexilant:

Dexilant (57,103 reports)

Bipolar disorder treatments and more:

Bipolar disorder (109,430 reports)

Browse all side effects of Dexilant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bipolar disorder:

Bipolar disorder (910 drugs)

Browse all the conditions that are associated with Bipolar disorder:

Bipolar disorder (1,231 conditions)

Related publications that referenced our studies

Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on dexlansoprazole (the active ingredients of Dexilant) and Dexilant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.