Dexilant and Nephrotic syndrome - a phase IV clinical study of FDA data

Summary:

Nephrotic syndrome is reported as a side effect among people who take Dexilant (dexlansoprazole), especially for people who are male, 40-49 old, have been taking the drug for 10+ years also take Prilosec, and have Pain.

The phase IV clinical study analyzes which people have Nephrotic syndrome when taking Dexilant. It is created by eHealthMe based on reports of 56,153 people who have side effects when taking Dexilant from the FDA, and is updated regularly.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

What is Nephrotic syndrome?

Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema) is found to be associated with 628 drugs and 1,070 conditions by eHealthMe. Check the latest studies of Nephrotic syndrome.

On Jul, 06, 2026

56,153 people reported to have side effects when taking Dexilant.
Among them, 30 people (0.05%) have Nephrotic syndrome.

Could Dexilant cause Nephrotic syndrome?

Among these 30 people:

How long have people been on Dexilant when they have Nephrotic syndrome? *

What is the gender of people who have Nephrotic syndrome when taking Dexilant? *

female: 41.67 %
male: 58.33 %

What is the age of people who have Nephrotic syndrome when taking Dexilant? *

What are other drugs people take besides Dexilant? *

What are other side effects people have besides Nephrotic syndrome? *

Chronic Kidney Disease: 30 people, 100.00%
Acute Kidney Failure: 26 people, 86.67%
High Blood Pressure: 13 people, 43.33%
Diabetic Nephropathy (diabetic kidney disease): 11 people, 36.67%
Nephropathy (damage to or disease of a kidney): 11 people, 36.67%
Interstitial Nephritis (inflammation of the kidney): 9 people, 30.00%
Renal Injury (kidney injury): 8 people, 26.67%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 8 people, 26.67%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 8 people, 26.67%
Kidney Infection: 8 people, 26.67%

What are the existing conditions these people have? *

Pain: 10 people, 33.33%
Hypersensitivity: 7 people, 23.33%
Renal Disorder (kidney disease): 6 people, 20.00%
Depression: 5 people, 16.67%
Gastric Ph Decreased: 4 people, 13.33%
Joint Pain: 4 people, 13.33%
High Blood Pressure: 3 people, 10.00%
Incontinence (lack of moderation or self-control): 3 people, 10.00%
Diabetes: 3 people, 10.00%
High Blood Cholesterol: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Dexilant and have Nephrotic syndrome?

- Check whether Nephrotic syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dexilant:

Dexilant (57,103 reports)

Browse all side effects of Dexilant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephrotic syndrome:

Nephrotic syndrome (628 drugs)

Browse all the conditions that are associated with Nephrotic syndrome:

Nephrotic syndrome (1,070 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dexlansoprazole (the active ingredients of Dexilant) and Dexilant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.