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Dexilant and Pemphigus - a phase IV clinical study of FDA data

Summary:

Pemphigus is reported as a side effect among people who take Dexilant (dexlansoprazole), especially for people who are female, 60+ old, also take Dilaudid, and have Itching.

The phase IV clinical study analyzes which people have Pemphigus when taking Dexilant. It is created by eHealthMe based on reports of 56,153 people who have side effects when taking Dexilant from the FDA, and is updated regularly.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

What is Pemphigus?

Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters) is found to be associated with 304 drugs and 304 conditions by eHealthMe. Check the latest studies of Pemphigus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

56,153 people reported to have side effects when taking Dexilant.
Among them, 17 people (0.03%) have Pemphigus.

Could Dexilant cause Pemphigus?

Among these 17 people:

What is the gender of people who have Pemphigus when taking Dexilant? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Pemphigus when taking Dexilant? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 0.0 %
  • 60+: 88.89 %

What are other drugs people take besides Dexilant? *

  1. Hydroxyzine: 15 people, 88.24%
  2. Dilaudid: 15 people, 88.24%
  3. Methylprednisolone Sodium Succinate: 14 people, 82.35%
  4. Vitamin D3: 14 people, 82.35%
  5. Prednisone: 14 people, 82.35%
  6. Oxazepam: 13 people, 76.47%
  7. Furosemide: 13 people, 76.47%
  8. Ezetimibe: 13 people, 76.47%
  9. Benadryl: 13 people, 76.47%
  10. Aspirin: 13 people, 76.47%

What are other side effects people have besides Pemphigus? *

  1. High Blood Pressure: 16 people, 94.12%
  2. Pemphigoid (tense blisters on the skin): 15 people, 88.24%
  3. Onychomadesis (a periodic idiopathic shedding of the nails): 15 people, 88.24%
  4. Blood Pressure Fluctuation: 15 people, 88.24%
  5. Blood Pressure Systolic Increased: 15 people, 88.24%
  6. Blood Pressure Systolic Abnormal: 4 people, 23.53%
  7. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 11.76%
  8. Dizziness: 2 people, 11.76%
  9. Wound: 1 person, 5.88%
  10. Fatigue (feeling of tiredness): 1 person, 5.88%

What are the existing conditions these people have? *

  1. Pain: 14 people, 82.35%
  2. Itching: 14 people, 82.35%
  3. Pemphigoid (tense blisters on the skin): 13 people, 76.47%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.88%
  6. Interstitial Lung Disease: 1 person, 5.88%
  7. Inflammation: 1 person, 5.88%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.88%
  9. Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 5.88%
  10. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Dexilant and have Pemphigus?

- Check whether Pemphigus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dexilant:

Pemphigus treatments and more:

How severe was Pemphigus and when was it recovered:

Expand to all the drugs that have ingredients of dexlansoprazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dexilant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pemphigus:

Browse all the conditions that are associated with Pemphigus:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on dexlansoprazole (the active ingredients of Dexilant) and Dexilant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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