Dexmedetomidine and Myoclonus - a phase IV clinical study of FDA data
Summary:
Myoclonus is reported as a side effect among people who take Dexmedetomidine (dexmedetomidine hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Propofol, and have Sedation.
The phase IV clinical study analyzes which people have Myoclonus when taking Dexmedetomidine. It is created by eHealthMe based on reports of 4,501 people who have side effects when taking Dexmedetomidine from the FDA, and is updated regularly.
What is Dexmedetomidine?
Dexmedetomidine has active ingredients of dexmedetomidine hydrochloride. eHealthMe is studying from 4,502 Dexmedetomidine users. Check the latest studies of Dexmedetomidine.
What is Myoclonus?
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles) is found to be associated with 759 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Myoclonus.
4,501 people reported to have side effects when taking Dexmedetomidine.
Among them, 45 people (1.0%) have Myoclonus.

Among these 45 people:
How long have people been on Dexmedetomidine when they have Myoclonus? *
- < 1 month: 50 %
- 1 - 6 months: 50 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Myoclonus when taking Dexmedetomidine? *
- female: 50 %
- male: 50 %
What is the age of people who have Myoclonus when taking Dexmedetomidine? *
- 0-1: 2.44 %
- 2-9: 2.44 %
- 10-19: 4.88 %
- 20-29: 0.0 %
- 30-39: 7.32 %
- 40-49: 14.63 %
- 50-59: 56.1 %
- 60+: 12.2 %
What are other drugs people take besides Dexmedetomidine? *
- Propofol: 18 people, 40.00%
- Morphine: 16 people, 35.56%
- Levetiracetam: 15 people, 33.33%
- Lorazepam: 15 people, 33.33%
- Lacosamide: 14 people, 31.11%
- Valproic Acid: 5 people, 11.11%
- Midazolam: 3 people, 6.67%
- Bupivacaine: 2 people, 4.44%
- Lasix: 2 people, 4.44%
- Oxycodone: 2 people, 4.44%
What are other side effects people have besides Myoclonus? *
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 4 people, 8.89%
- Delirium (wild excitement): 4 people, 8.89%
- Tachyphylaxis (a medical term describing an acute (sudden) decrease in the response to a drug after its administration): 3 people, 6.67%
- Drug Level Increased: 3 people, 6.67%
- Agitation (state of anxiety or nervous excitement): 2 people, 4.44%
- Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 4.44%
- Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 2 people, 4.44%
- Confusional State: 2 people, 4.44%
- Disturbance In Attention: 1 person, 2.22%
- Autonomic Nervous System Imbalance (autonomic nervous system is of net equal emphasis): 1 person, 2.22%
What are the existing conditions these people have? *
- Sedation: 14 people, 31.11%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 15.56%
- Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 6 people, 13.33%
- Muscle Twitching: 5 people, 11.11%
- Stress And Anxiety: 3 people, 6.67%
- Pain: 3 people, 6.67%
- Sleep Disorder: 2 people, 4.44%
- Respiratory Tract Infection: 2 people, 4.44%
- Septic Shock (shock due to blood infection): 1 person, 2.22%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 2.22%
* Approximation only. Some reports may have incomplete information.
Do you take Dexmedetomidine and have Myoclonus?
- Check whether Myoclonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Dexmedetomidine:
- Dexmedetomidine (4,502 reports)
Myoclonus treatments and more:
- Myoclonus (14,211 reports)
How severe was Myoclonus and when was it recovered:
Expand to all the drugs that have ingredients of dexmedetomidine hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Dexmedetomidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Myoclonus:
- Myoclonus (759 drugs)
Browse all the conditions that are associated with Myoclonus:
- Myoclonus (1,139 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on dexmedetomidine hydrochloride (the active ingredients of Dexmedetomidine) and Dexmedetomidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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