Diazepam and Negativism - a phase IV clinical study of FDA data

Summary:

Negativism is reported as a side effect among people who take Diazepam (diazepam), especially for people who are female, 30-39 old, also take Risperidone, and have Psychotic disorder.

The phase IV clinical study analyzes which people have Negativism when taking Diazepam. It is created by eHealthMe based on reports of 105,904 people who have side effects when taking Diazepam from the FDA, and is updated regularly.

What is Diazepam?

Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.

What is Negativism?

Negativism (negative thoughts) is found to be associated with 77 drugs and 234 conditions by eHealthMe. Check the latest studies of Negativism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

105,904 people reported to have side effects when taking Diazepam.
Among them, 31 people (0.03%) have Negativism.

Could Diazepam cause Negativism?

Among these 31 people:

What is the gender of people who have Negativism when taking Diazepam? *

  • female: 78.57 %
  • male: 21.43 %

What is the age of people who have Negativism when taking Diazepam? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.69 %
  • 20-29: 23.08 %
  • 30-39: 34.62 %
  • 40-49: 19.23 %
  • 50-59: 7.69 %
  • 60+: 7.69 %

What are other drugs people take besides Diazepam? *

  1. Haloperidol: 5 people, 16.13%
  2. Risperidone: 5 people, 16.13%
  3. Haldol: 4 people, 12.90%
  4. Zopiclone: 4 people, 12.90%
  5. Amisulpride: 4 people, 12.90%
  6. Carbamazepine: 4 people, 12.90%
  7. Surmontil: 3 people, 9.68%
  8. Clozapine: 3 people, 9.68%
  9. Promazine Hydrochloride: 3 people, 9.68%
  10. Zyprexa: 3 people, 9.68%

What are other side effects people have besides Negativism? *

  1. Aggression: 17 people, 54.84%
  2. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 11 people, 35.48%
  3. Muscle Rigidity (muscle stiffness): 9 people, 29.03%
  4. Insomnia (sleeplessness): 9 people, 29.03%
  5. Suicidal Ideation: 9 people, 29.03%
  6. Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 8 people, 25.81%
  7. Agitation (state of anxiety or nervous excitement): 8 people, 25.81%
  8. Stupor (lack of critical cognitive function and level of consciousness): 8 people, 25.81%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 22.58%
  10. Drowsiness: 7 people, 22.58%

What are the existing conditions these people have? *

  1. Psychotic Disorder: 6 people, 19.35%
  2. Encephalitis Autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain): 5 people, 16.13%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 16.13%
  4. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 4 people, 12.90%
  5. Aggression: 3 people, 9.68%
  6. Psychomotor Hyperactivity (feelings of extreme restlessness): 3 people, 9.68%
  7. Depression: 3 people, 9.68%
  8. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 9.68%
  9. Mania (a state of abnormally elevated or irritable mood): 3 people, 9.68%
  10. Galactorrhea (secretion of breast milk in men): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Diazepam and have Negativism?

- Check whether Negativism is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Diazepam:

Negativism treatments and more:

How severe was Negativism and when was it recovered:

Expand to all the drugs that have ingredients of diazepam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Negativism:

Browse all the conditions that are associated with Negativism:


How the study uses the data?

The study uses data from the FDA. It is based on diazepam (the active ingredients of Diazepam) and Diazepam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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