Digoxin and Areflexia - a phase IV clinical study of FDA data
Summary:
Areflexia is reported as a side effect among people who take Digoxin (digoxin), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Furosemide, and have Dementia alzheimer's type.
The phase IV clinical study analyzes which people have Areflexia when taking Digoxin. It is created by eHealthMe based on reports of 92,292 people who have side effects when taking Digoxin from the FDA, and is updated regularly.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
What is Areflexia?
Areflexia (absence of a reflex) is found to be associated with 433 drugs and 720 conditions by eHealthMe. Check the latest studies of Areflexia.
92,292 people reported to have side effects when taking Digoxin.
Among them, 32 people (0.03%) have Areflexia.

Among these 32 people:
How long have people been on Digoxin when they have Areflexia? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 11.11 %
- 1 - 2 years: 11.11 %
- 2 - 5 years: 55.56 %
- 5 - 10 years: 22.22 %
- 10+ years: 0.0 %
What is the gender of people who have Areflexia when taking Digoxin? *
- female: 59.38 %
- male: 40.62 %
What is the age of people who have Areflexia when taking Digoxin? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 11.11 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 14.81 %
- 60+: 74.07 %
What are other drugs people take besides Digoxin? *
- Furosemide: 14 people, 43.75%
- Aspirin: 8 people, 25.00%
- Warfarin Sodium: 7 people, 21.88%
- Lasix: 6 people, 18.75%
- Cordarone: 5 people, 15.62%
- Nitroglycerin: 5 people, 15.62%
- Zocor: 4 people, 12.50%
- Plavix: 4 people, 12.50%
- Coumadin: 4 people, 12.50%
- Metronidazole: 4 people, 12.50%
What are other side effects people have besides Areflexia? *
- High Blood Pressure: 9 people, 28.12%
- Weakness: 9 people, 28.12%
- Malaise (a feeling of general discomfort or uneasiness): 7 people, 21.88%
- Fatigue (feeling of tiredness): 7 people, 21.88%
- Arrhythmias (irregular heartbeat): 7 people, 21.88%
- Anaemia (lack of blood): 7 people, 21.88%
- Fall: 6 people, 18.75%
- Dyspnea (difficult or laboured breathing): 6 people, 18.75%
- Cardiac Failure Congestive: 6 people, 18.75%
- Nausea And Vomiting: 6 people, 18.75%
What are the existing conditions these people have? *
- Pyogenic Liver Abscess (liver abscess caused by bacteria): 3 people, 9.38%
- Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 9.38%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 3.12%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 3.12%
- Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 3.12%
- Insomnia (sleeplessness): 1 person, 3.12%
- Hyperthyroidism (over activity of the thyroid gland): 1 person, 3.12%
- High Blood Pressure: 1 person, 3.12%
- Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 1 person, 3.12%
- Constipation: 1 person, 3.12%
* Approximation only. Some reports may have incomplete information.
Do you take Digoxin and have Areflexia?
- Check whether Areflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Digoxin:
- Digoxin (93,740 reports)
Areflexia treatments and more:
- Areflexia (3,364 reports)
How severe was Areflexia and when was it recovered:
Expand to all the drugs that have ingredients of digoxin:
- Areflexia and drugs with ingredients of digoxin (35 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Areflexia:
- Areflexia (433 drugs)
Browse all the conditions that are associated with Areflexia:
- Areflexia (720 conditions)
Related publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin (the active ingredients of Digoxin) and Digoxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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