Dilantin-125 and Hypersensitivity - a phase IV clinical study of FDA data

Summary:

Hypersensitivity is reported as a side effect among people who take Dilantin-125 (phenytoin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Dilantin, and have Convulsion.

The phase IV clinical study analyzes which people have Hypersensitivity when taking Dilantin-125. It is created by eHealthMe based on reports of 2,125 people who have side effects when taking Dilantin-125 from the FDA, and is updated regularly.

What is Dilantin-125?

Dilantin-125 has active ingredients of phenytoin. It is often used in epilepsy. eHealthMe is studying from 2,213 Dilantin-125 users. Check the latest studies of Dilantin-125.

What is Hypersensitivity?

Hypersensitivity is found to be associated with 2,754 drugs and 2,913 conditions by eHealthMe. Check the latest studies of Hypersensitivity.



On Jul, 11, 2026

2,125 people reported to have side effects when taking Dilantin-125.
Among them, 34 people (1.6%) have Hypersensitivity.

Could Dilantin-125 cause Hypersensitivity?

Among these 34 people:

How long have people been on Dilantin-125 when they have Hypersensitivity? *

  • < 1 month: 77.78 %
  • 1 - 6 months: 22.22 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypersensitivity when taking Dilantin-125? *

  • female: 83.87 %
  • male: 16.13 %

What is the age of people who have Hypersensitivity when taking Dilantin-125? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5 %
  • 20-29: 0.0 %
  • 30-39: 10 %
  • 40-49: 10 %
  • 50-59: 5 %
  • 60+: 70 %

What are other drugs people take besides Dilantin-125? *

  1. Dilantin: 9 people, 26.47%
  2. Lasix: 7 people, 20.59%
  3. Lisinopril: 7 people, 20.59%
  4. Zofran: 6 people, 17.65%
  5. Phenytoin: 6 people, 17.65%
  6. Benadryl: 6 people, 17.65%
  7. Clonidine: 6 people, 17.65%
  8. Miconazole Nitrate: 6 people, 17.65%
  9. Nitroglycerin: 6 people, 17.65%
  10. Lopressor: 6 people, 17.65%

What are other side effects people have besides Hypersensitivity? *

  1. Dyspnea (difficult or laboured breathing): 9 people, 26.47%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 9 people, 26.47%
  3. Acute Kidney Failure: 7 people, 20.59%
  4. Erythema Multiforme (a type of hypersensitivity reaction): 7 people, 20.59%
  5. Scar: 6 people, 17.65%
  6. Vision Blurred: 6 people, 17.65%
  7. Dry Eyes (lack of adequate tears): 6 people, 17.65%
  8. Oedema Peripheral (superficial swelling): 6 people, 17.65%
  9. Swallowing Difficulty: 6 people, 17.65%
  10. Encephalopathy (functioning of the brain is affected by some agent or condition): 6 people, 17.65%

What are the existing conditions these people have? *

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 16 people, 47.06%
  2. High Blood Pressure: 3 people, 8.82%
  3. Depression: 1 person, 2.94%
  4. Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 1 person, 2.94%
  5. Cerebral Atrophy (decrement in size of brain): 1 person, 2.94%
  6. Aneurysm (enlargement of an artery caused by a weakening of the artery wall): 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Dilantin-125 and have Hypersensitivity?

- Check whether Hypersensitivity is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilantin-125:

Hypersensitivity treatments and more:

How severe was Hypersensitivity and when was it recovered:

Expand to all the drugs that have ingredients of phenytoin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dilantin-125:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypersensitivity:

Browse all the conditions that are associated with Hypersensitivity:

Related publications that referenced our studies

  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .
  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on phenytoin (the active ingredients of Dilantin-125) and Dilantin-125 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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