Dilaudid and Injection site irritation - a phase IV clinical study of FDA data

Summary:

Injection site irritation is reported as a side effect among people who take Dilaudid (hydromorphone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Deep venous thrombosis.

The phase IV clinical study analyzes which people have Injection site irritation when taking Dilaudid. It is created by eHealthMe based on reports of 95,518 people who have side effects when taking Dilaudid from the FDA, and is updated regularly.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

What is Injection site irritation?

Injection site irritation is found to be associated with 452 drugs and 511 conditions by eHealthMe. Check the latest studies of Injection site irritation.



On Jul, 14, 2026

95,518 people reported to have side effects when taking Dilaudid.
Among them, 17 people (0.02%) have Injection site irritation.

Could Dilaudid cause Injection site irritation?

Among these 17 people:

How long have people been on Dilaudid when they have Injection site irritation? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Injection site irritation when taking Dilaudid? *

  • female: 88.24 %
  • male: 11.76 %

What is the age of people who have Injection site irritation when taking Dilaudid? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 33.33 %
  • 60+: 33.33 %

What are other drugs people take besides Dilaudid? *

  1. Coumadin: 13 people, 76.47%
  2. Zofran: 12 people, 70.59%
  3. Lovenox: 12 people, 70.59%
  4. Ambien: 12 people, 70.59%
  5. Ativan: 12 people, 70.59%
  6. Tylenol: 12 people, 70.59%
  7. Pitocin: 12 people, 70.59%
  8. Demerol: 12 people, 70.59%
  9. Percocet: 12 people, 70.59%
  10. Xanax: 12 people, 70.59%

What are other side effects people have besides Injection site irritation? *

  1. Fatigue (feeling of tiredness): 13 people, 76.47%
  2. Joint Pain: 13 people, 76.47%
  3. White Blood Cell Count Increased: 12 people, 70.59%
  4. Placental Infarction (interruption of blood supply to a part of the placenta, causing its cells to die): 12 people, 70.59%
  5. Haematocrit Decreased: 12 people, 70.59%
  6. Haemoglobin Decreased: 12 people, 70.59%
  7. Head Injury: 12 people, 70.59%
  8. Hospitalisation: 12 people, 70.59%
  9. Chorioamnionitis (inflammation of the fetal membranes (amnion and chorion) due to a bacterial infection): 12 people, 70.59%
  10. Liver Function Test Abnormal: 12 people, 70.59%

What are the existing conditions these people have? *

  1. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 23.53%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 5.88%
  3. Osteoporosis (bones weak and more likely to break): 1 person, 5.88%
  4. Diarrhea: 1 person, 5.88%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Dilaudid and have Injection site irritation?

- Check whether Injection site irritation is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilaudid:

Injection site irritation treatments and more:

How severe was Injection site irritation and when was it recovered:

Expand to all the drugs that have ingredients of hydromorphone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dilaudid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site irritation:

Browse all the conditions that are associated with Injection site irritation:


How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride (the active ingredients of Dilaudid) and Dilaudid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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