Dilaudid and Progressive multifocal leukoencephalopathy - a phase IV clinical study of FDA data

Summary:

Progressive multifocal leukoencephalopathy is reported as a side effect among people who take Dilaudid (hydromorphone hydrochloride), especially for people who are female, 50-59 old, also take Cymbalta, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Progressive multifocal leukoencephalopathy when taking Dilaudid. It is created by eHealthMe based on reports of 95,518 people who have side effects when taking Dilaudid from the FDA, and is updated regularly.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

What is Progressive multifocal leukoencephalopathy?

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells) is found to be associated with 592 drugs and 921 conditions by eHealthMe. Check the latest studies of Progressive multifocal leukoencephalopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

95,518 people reported to have side effects when taking Dilaudid.
Among them, 32 people (0.03%) have Progressive multifocal leukoencephalopathy.

Could Dilaudid cause Progressive multifocal leukoencephalopathy?

Among these 32 people:

What is the gender of people who have Progressive multifocal leukoencephalopathy when taking Dilaudid? *

female: 61.54 %
male: 38.46 %

What is the age of people who have Progressive multifocal leukoencephalopathy when taking Dilaudid? *

What are other drugs people take besides Dilaudid? *

Clonazepam: 20 people, 62.50%
Cymbalta: 20 people, 62.50%
Zopiclone: 19 people, 59.38%
Prevacid: 19 people, 59.38%
Aripiprazole: 19 people, 59.38%
Atenolol: 19 people, 59.38%
Cetirizine Hydrochloride: 19 people, 59.38%
Famotidine: 19 people, 59.38%
Medrol: 19 people, 59.38%
Claritin: 18 people, 56.25%

What are other side effects people have besides Progressive multifocal leukoencephalopathy? *

Diarrhea: 20 people, 62.50%
Dizziness: 20 people, 62.50%
Hypotension (abnormally low blood pressure): 20 people, 62.50%
Weakness: 20 people, 62.50%
Fatigue (feeling of tiredness): 20 people, 62.50%
Fall: 20 people, 62.50%
Depression: 20 people, 62.50%
Swallowing Difficulty: 20 people, 62.50%
Dry Mouth: 19 people, 59.38%
Drug Hypersensitivity: 19 people, 59.38%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 46.88%
Hypersensitivity: 12 people, 37.50%
Tremor (trembling or shaking movements in one or more parts of your body): 10 people, 31.25%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 31.25%
Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx): 10 people, 31.25%
High Blood Pressure: 10 people, 31.25%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 10 people, 31.25%
Sleep Disorder: 9 people, 28.12%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 3.12%
Tonsil Cancer: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Dilaudid and have Progressive multifocal leukoencephalopathy?

- Check whether Progressive multifocal leukoencephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilaudid:

Dilaudid (96,466 reports)

Progressive multifocal leukoencephalopathy treatments and more:

Progressive multifocal leukoencephalopathy (13,731 reports)

How severe was Progressive multifocal leukoencephalopathy and when was it recovered:

Progressive multifocal leukoencephalopathy in Dilaudid

Expand to all the drugs that have ingredients of hydromorphone hydrochloride:

Progressive multifocal leukoencephalopathy and drugs with ingredients of hydromorphone hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dilaudid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Progressive multifocal leukoencephalopathy:

Progressive multifocal leukoencephalopathy (592 drugs)

Browse all the conditions that are associated with Progressive multifocal leukoencephalopathy:

Progressive multifocal leukoencephalopathy (921 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride (the active ingredients of Dilaudid) and Dilaudid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.