Diovan and Skin induration - a phase IV clinical study of FDA data
Summary:
Skin induration is reported as a side effect among people who take Diovan (valsartan), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Magnevist, and have Nuclear magnetic resonance imaging brain.
The phase IV clinical study analyzes which people have Skin induration when taking Diovan. It is created by eHealthMe based on reports of 80,750 people who have side effects when taking Diovan from the FDA, and is updated regularly.
What is Diovan?
Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.
What is Skin induration?
Skin induration (an abnormally hard spot or area on the skin) is found to be associated with 519 drugs and 501 conditions by eHealthMe. Check the latest studies of Skin induration.
80,750 people reported to have side effects when taking Diovan.
Among them, 76 people (0.09%) have Skin induration.

Among these 76 people:
How long have people been on Diovan when they have Skin induration? *
- < 1 month: 33.33 %
- 1 - 6 months: 66.67 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Skin induration when taking Diovan? *
- female: 60.53 %
- male: 39.47 %
What is the age of people who have Skin induration when taking Diovan? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 3.03 %
- 30-39: 4.55 %
- 40-49: 12.12 %
- 50-59: 51.52 %
- 60+: 28.79 %
What are other drugs people take besides Diovan? *
- Magnevist: 67 people, 88.16%
- Omniscan: 53 people, 69.74%
- Optimark: 49 people, 64.47%
- Multihance: 42 people, 55.26%
- Prohance: 42 people, 55.26%
- Norvasc: 35 people, 46.05%
- Renagel: 32 people, 42.11%
- Phoslo: 29 people, 38.16%
- Toprol-Xl: 25 people, 32.89%
- Aspirin: 24 people, 31.58%
What are other side effects people have besides Skin induration? *
- Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 67 people, 88.16%
- Pain: 61 people, 80.26%
- Rashes (redness): 47 people, 61.84%
- Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 44 people, 57.89%
- Oedema Peripheral (superficial swelling): 39 people, 51.32%
- General Physical Health Deterioration (weak health status): 39 people, 51.32%
- Mobility Decreased (ability to move is reduced): 38 people, 50.00%
- Weakness: 34 people, 44.74%
- Skin Hypertrophy (skin cells enlarges): 34 people, 44.74%
- Skin Discoloration: 33 people, 43.42%
What are the existing conditions these people have? *
- Nuclear Magnetic Resonance Imaging Brain: 36 people, 47.37%
- Nuclear Magnetic Resonance Imaging Abdominal: 30 people, 39.47%
- Diabetes: 8 people, 10.53%
- Pain: 5 people, 6.58%
- Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 5 people, 6.58%
- Blood Phosphorus Increased: 5 people, 6.58%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.26%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 5.26%
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 5.26%
- Chest Pain: 2 people, 2.63%
* Approximation only. Some reports may have incomplete information.
Do you take Diovan and have Skin induration?
- Check whether Skin induration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Diovan:
- Diovan (83,153 reports)
Skin induration treatments and more:
- Skin induration (3,079 reports)
How severe was Skin induration and when was it recovered:
Expand to all the drugs that have ingredients of valsartan:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Diovan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Skin induration:
- Skin induration (519 drugs)
Browse all the conditions that are associated with Skin induration:
- Skin induration (501 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on valsartan (the active ingredients of Diovan) and Diovan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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