Diphen and Hyperventilation - a phase IV clinical study of FDA data

Summary:

Hyperventilation is reported as a side effect among people who take Diphen (diphenhydramine hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Ativan, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Hyperventilation when taking Diphen. It is created by eHealthMe based on reports of 113,958 people who have side effects when taking Diphen from the FDA, and is updated regularly.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,430 Diphen users. Check the latest studies of Diphen.

What is Hyperventilation?

Hyperventilation is found to be associated with 816 drugs and 1,437 conditions by eHealthMe. Check the latest studies of Hyperventilation.

On Dec, 06, 2025

113,958 people reported to have side effects when taking Diphen.
Among them, 64 people (0.06%) have Hyperventilation.

Among these 64 people:

* Approximation only. Some reports may have incomplete information.

Do you take Diphen and have Hyperventilation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Diphen:

Diphen (115,430 reports)

Hyperventilation treatments and more:

Hyperventilation (8,309 reports)

How severe was Hyperventilation and when was it recovered:

Hyperventilation in Diphen

Expand to all the drugs that have ingredients of diphenhydramine hydrochloride:

Hyperventilation and drugs with ingredients of diphenhydramine hydrochloride (173 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Diphen side effects:

Browse all side effects of Diphen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Hyperventilation:

Browse all the drugs that are associated with Hyperventilation:

Hyperventilation (816 drugs)

Common conditions associated with Hyperventilation:

Asthma: 396 reports
Bronchial asthma: 395 reports
Depression aggravated: 354 reports
Antidepressant therapy: 352 reports
Hypertension: 345 reports
Htn: 344 reports
Pain: 316 reports
Alternative medicine - pain relief: 306 reports
Ms hug: 237 reports
Anxiety aggravated: 196 reports

Browse all the conditions that are associated with Hyperventilation:

Hyperventilation (1,437 conditions)

Drugs similar to Diphen and Hyperventilation :

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Diphen) and Diphen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.