Divalproex sodium and Bleeding disorders - a phase IV clinical study of FDA data

Summary:

Bleeding disorders is reported as a side effect among people who take Divalproex sodium (divalproex sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Diazepam, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Bleeding disorders when taking Divalproex sodium. It is created by eHealthMe based on reports of 9,295 people who have side effects when taking Divalproex sodium from the FDA, and is updated regularly.

What is Divalproex sodium?

Divalproex sodium has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 9,483 Divalproex sodium users. Check the latest studies of Divalproex sodium.

What is Bleeding disorders?

Bleeding disorders is found to be associated with 1,189 drugs and 1,649 conditions by eHealthMe. Check the latest studies of Bleeding disorders.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

9,295 people reported to have side effects when taking Divalproex sodium.
Among them, 18 people (0.19%) have Bleeding disorders.

Could Divalproex sodium cause Bleeding disorders?

Among these 18 people:

How long have people been on Divalproex sodium when they have Bleeding disorders? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bleeding disorders when taking Divalproex sodium? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Bleeding disorders when taking Divalproex sodium? *

  • 0-1: 7.69 %
  • 2-9: 23.08 %
  • 10-19: 23.08 %
  • 20-29: 7.69 %
  • 30-39: 7.69 %
  • 40-49: 0.0 %
  • 50-59: 7.69 %
  • 60+: 23.08 %

What are other drugs people take besides Divalproex sodium? *

  1. Cosentyx: 2 people, 11.11%
  2. Valproic Acid: 2 people, 11.11%
  3. Tramadol: 2 people, 11.11%
  4. Temazepam: 2 people, 11.11%
  5. Gabapentin: 2 people, 11.11%
  6. Diazepam: 2 people, 11.11%
  7. Zometa: 1 person, 5.56%
  8. Ibuprofen: 1 person, 5.56%
  9. Hydrocodone: 1 person, 5.56%
  10. Hydrochlorothiazide: 1 person, 5.56%

What are other side effects people have besides Bleeding disorders? *

  1. Thrombocytopenia (decrease of platelets in blood): 4 people, 22.22%
  2. Pain: 3 people, 16.67%
  3. Anaemia (lack of blood): 3 people, 16.67%
  4. Fever: 3 people, 16.67%
  5. Pain In Extremity: 2 people, 11.11%
  6. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 11.11%
  7. Rashes (redness): 2 people, 11.11%
  8. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 11.11%
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 11.11%
  10. Pancreatitis Acute (sudden inflammation of pancreas): 2 people, 11.11%

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 11.11%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 11.11%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 5.56%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
  5. Multiple Myeloma (cancer of the plasma cells): 1 person, 5.56%
  6. Fever: 1 person, 5.56%
  7. Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 5.56%
  8. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Divalproex sodium and have Bleeding disorders?

- Check whether Bleeding disorders is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Divalproex sodium:

Bleeding disorders treatments and more:

How severe was Bleeding disorders and when was it recovered:

Expand to all the drugs that have ingredients of divalproex sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Divalproex sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bleeding disorders:

Browse all the conditions that are associated with Bleeding disorders:


How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Divalproex sodium) and Divalproex sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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