Divalproex sodium and Deep venous thrombosis - a phase IV clinical study of FDA data

Summary:

Deep venous thrombosis is reported as a side effect among people who take Divalproex sodium (divalproex sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Depakote, and have Prostate cancer.

The phase IV clinical study analyzes which people have Deep venous thrombosis when taking Divalproex sodium. It is created by eHealthMe based on reports of 9,295 people who have side effects when taking Divalproex sodium from the FDA, and is updated regularly.

What is Divalproex sodium?

Divalproex sodium has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 9,483 Divalproex sodium users. Check the latest studies of Divalproex sodium.

What is Deep venous thrombosis?

Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis) is found to be associated with 2,070 drugs and 2,964 conditions by eHealthMe. Check the latest studies of Deep venous thrombosis.

On Jul, 17, 2026

9,295 people reported to have side effects when taking Divalproex sodium.
Among them, 43 people (0.46%) have Deep venous thrombosis.

Could Divalproex sodium cause Deep venous thrombosis?

Among these 43 people:

How long have people been on Divalproex sodium when they have Deep venous thrombosis? *

What is the gender of people who have Deep venous thrombosis when taking Divalproex sodium? *

female: 39.53 %
male: 60.47 %

What is the age of people who have Deep venous thrombosis when taking Divalproex sodium? *

What are other drugs people take besides Divalproex sodium? *

Depakote: 18 people, 41.86%
Simvastatin: 17 people, 39.53%
Vicodin: 16 people, 37.21%
Decadron: 15 people, 34.88%
Zometa: 15 people, 34.88%
Hydrochlorothiazide: 15 people, 34.88%
Diazepam: 13 people, 30.23%
Acetaminophen And Hydrocodone Bitartrate: 13 people, 30.23%
Celebrex: 12 people, 27.91%
Fish Oil: 12 people, 27.91%

What are other side effects people have besides Deep venous thrombosis? *

Injury: 20 people, 46.51%
Oedema Peripheral (superficial swelling): 19 people, 44.19%
Pain: 18 people, 41.86%
Fainting (loss of consciousness and postural tone): 17 people, 39.53%
Fever: 16 people, 37.21%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 16 people, 37.21%
Anaemia (lack of blood): 16 people, 37.21%
Osteomyelitis (infection of bone): 15 people, 34.88%
Osteonecrosis Of Jaw (death of bone of jaw): 15 people, 34.88%
Pain In Jaw: 15 people, 34.88%

What are the existing conditions these people have? *

Prostate Cancer: 10 people, 23.26%
Nausea (feeling of having an urge to vomit): 9 people, 20.93%
Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 6 people, 13.95%
Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 13.95%
Depression: 6 people, 13.95%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.95%
High Blood Pressure: 5 people, 11.63%
Sleep Disorder: 4 people, 9.30%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 9.30%
Birth Control: 4 people, 9.30%

* Approximation only. Some reports may have incomplete information.

Do you take Divalproex sodium and have Deep venous thrombosis?

- Check whether Deep venous thrombosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Divalproex sodium:

Divalproex sodium (9,483 reports)

Browse all side effects of Divalproex sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Deep venous thrombosis:

Deep venous thrombosis (2,070 drugs)

Browse all the conditions that are associated with Deep venous thrombosis:

Deep venous thrombosis (2,964 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Divalproex sodium) and Divalproex sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.