Divigel and Abdominal pain - a phase IV clinical study of FDA data

Summary:

Abdominal pain is reported as a side effect among people who take Divigel (estradiol), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Vitamin B12, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Abdominal pain when taking Divigel. It is created by eHealthMe based on reports of 840 people who have side effects when taking Divigel from the FDA, and is updated regularly.

What is Divigel?

Divigel has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 894 Divigel users. Check the latest studies of Divigel.

What is Abdominal pain?

Abdominal pain is found to be associated with 3,227 drugs and 5,743 conditions by eHealthMe. Check the latest studies of Abdominal pain.

On Jul, 14, 2026

840 people reported to have side effects when taking Divigel.
Among them, 14 people (1.67%) have Abdominal pain.

Among these 14 people:

How long have people been on Divigel when they have Abdominal pain? *

What is the gender of people who have Abdominal pain when taking Divigel? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Abdominal pain when taking Divigel? *

What are other drugs people take besides Divigel? *

What are other side effects people have besides Abdominal pain? *

Nausea (feeling of having an urge to vomit): 5 people, 35.71%
Diarrhea: 5 people, 35.71%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 35.71%
Fatigue (feeling of tiredness): 4 people, 28.57%
Vaginal Bleeding: 4 people, 28.57%
Headache (pain in head): 4 people, 28.57%
Influenza Like Illness: 3 people, 21.43%
Chills (felling of cold): 3 people, 21.43%
Migraine (headache): 3 people, 21.43%
Joint Pain: 3 people, 21.43%

What are the existing conditions these people have? *

Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 21.43%
Testis Cancer (testes cancer): 1 person, 7.14%
Quit Smoking: 1 person, 7.14%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1 person, 7.14%
Endocrine Disorder (endocrine diseases are disorders of the endocrine system): 1 person, 7.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.14%
Atrophic Vulvovaginitis (inflammation of the vulva): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Divigel and have Abdominal pain?

- Check whether Abdominal pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Divigel:

Divigel (894 reports)

Abdominal pain treatments and more:

Abdominal pain (286,410 reports)

Browse all side effects of Divigel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abdominal pain:

Abdominal pain (3,227 drugs)

Browse all the conditions that are associated with Abdominal pain:

Abdominal pain (5,743 conditions)

Related publications that referenced our studies

Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Divigel) and Divigel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.