Doxepin hydrochloride and Itching - a phase IV clinical study of FDA data

Summary:

Itching is reported as a side effect among people who take Doxepin hydrochloride (doxepin hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Hydroxyzine, and have Urticaria.

The phase IV clinical study analyzes which people have Itching when taking Doxepin hydrochloride. It is created by eHealthMe based on reports of 1,605 people who have side effects when taking Doxepin hydrochloride from the FDA, and is updated regularly.

What is Doxepin hydrochloride?

Doxepin hydrochloride has active ingredients of doxepin hydrochloride. It is often used in insomnia. eHealthMe is studying from 2,323 Doxepin hydrochloride users. Check the latest studies of Doxepin hydrochloride.

What is Itching?

Itching is found to be associated with 3,210 drugs and 4,533 conditions by eHealthMe. Check the latest studies of Itching.

On Jul, 14, 2026

1,605 people reported to have side effects when taking Doxepin hydrochloride.
Among them, 87 people (5.42%) have Itching.

Could Doxepin hydrochloride cause Itching?

Among these 87 people:

How long have people been on Doxepin hydrochloride when they have Itching? *

What is the gender of people who have Itching when taking Doxepin hydrochloride? *

female: 92.59 %
male: 7.41 %

What is the age of people who have Itching when taking Doxepin hydrochloride? *

What are other drugs people take besides Doxepin hydrochloride? *

What are other side effects people have besides Itching? *

Urticaria (rash of round, red welts on the skin that itch intensely): 35 people, 40.23%
Rashes (redness): 34 people, 39.08%
Fatigue (feeling of tiredness): 31 people, 35.63%
Diarrhea: 24 people, 27.59%
Pain In Extremity: 20 people, 22.99%
Suicidal Ideation: 18 people, 20.69%
Abdominal Pain Upper: 17 people, 19.54%
Hair Loss: 17 people, 19.54%
Drug Ineffective: 16 people, 18.39%
Nausea (feeling of having an urge to vomit): 15 people, 17.24%

What are the existing conditions these people have? *

Urticaria (rash of round, red welts on the skin that itch intensely): 11 people, 12.64%
Gout (uric acid crystals building up in the body): 6 people, 6.90%
High Blood Pressure: 6 people, 6.90%
Stress And Anxiety: 6 people, 6.90%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 4.60%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 3.45%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 3.45%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 3.45%
Cardiac Disorder: 3 people, 3.45%
Immunodeficiency: 3 people, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Doxepin hydrochloride and have Itching?

- Check whether Itching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxepin hydrochloride:

Doxepin hydrochloride (2,323 reports)

Itching treatments and more:

Itching (398,821 reports)

Browse all side effects of Doxepin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Itching:

Itching (3,210 drugs)

Browse all the conditions that are associated with Itching:

Itching (4,533 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxepin hydrochloride (the active ingredients of Doxepin hydrochloride) and Doxepin hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.