Drisdol and Mental status changes - a phase IV clinical study of FDA data

Summary:

Mental status changes is reported as a side effect among people who take Drisdol (ergocalciferol), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Ativan, and have Depression.

The phase IV clinical study analyzes which people have Mental status changes when taking Drisdol. It is created by eHealthMe based on reports of 1,686 people who have side effects when taking Drisdol from the FDA, and is updated regularly.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,741 Drisdol users. Check the latest studies of Drisdol.

What is Mental status changes?

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) is found to be associated with 1,491 drugs and 1,760 conditions by eHealthMe. Check the latest studies of Mental status changes.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

1,686 people reported to have side effects when taking Drisdol.
Among them, 21 people (1.25%) have Mental status changes.

Could Drisdol cause Mental status changes?

Among these 21 people:

How long have people been on Drisdol when they have Mental status changes? *

What is the gender of people who have Mental status changes when taking Drisdol? *

female: 41.18 %
male: 58.82 %

What is the age of people who have Mental status changes when taking Drisdol? *

What are other drugs people take besides Drisdol? *

What are other side effects people have besides Mental status changes? *

Weakness: 14 people, 66.67%
Nausea (feeling of having an urge to vomit): 13 people, 61.90%
Memory Loss: 11 people, 52.38%
Confusional State: 11 people, 52.38%
Stress And Anxiety: 11 people, 52.38%
Blood Calcium Decreased: 10 people, 47.62%
High Blood Pressure: 10 people, 47.62%
Fatigue (feeling of tiredness): 10 people, 47.62%
Depression: 9 people, 42.86%
Visual Impairment: 7 people, 33.33%

What are the existing conditions these people have? *

Depression: 8 people, 38.10%
Constipation: 6 people, 28.57%
Stress And Anxiety: 6 people, 28.57%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 28.57%
Nausea (feeling of having an urge to vomit): 5 people, 23.81%
Muscle Spasms (muscle contraction): 4 people, 19.05%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 19.05%
Dehydration (dryness resulting from the removal of water): 4 people, 19.05%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 19.05%
Agitation (state of anxiety or nervous excitement): 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

Do you take Drisdol and have Mental status changes?

- Check whether Mental status changes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Drisdol:

Drisdol (1,741 reports)

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental status changes:

Mental status changes (1,491 drugs)

Browse all the conditions that are associated with Mental status changes:

Mental status changes (1,760 conditions)

Related publications that referenced our studies

Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol (the active ingredients of Drisdol) and Drisdol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.