Dulcolax and Ankylosing spondylitis - a phase IV clinical study of FDA data

Summary:

Ankylosing spondylitis is reported as a side effect among people who take Dulcolax (bisacodyl), especially for people who are male, 50-59 old, also take Lidoderm, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Ankylosing spondylitis when taking Dulcolax. It is created by eHealthMe based on reports of 12,769 people who have side effects when taking Dulcolax from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Ankylosing spondylitis?

Ankylosing spondylitis (type of arthritis affecting the spine) is found to be associated with 748 drugs and 1,048 conditions by eHealthMe. Check the latest studies of Ankylosing spondylitis.

On Jul, 05, 2026

12,769 people reported to have side effects when taking Dulcolax.
Among them, 16 people (0.13%) have Ankylosing spondylitis.

Could Dulcolax cause Ankylosing spondylitis?

Among these 16 people:

What is the gender of people who have Ankylosing spondylitis when taking Dulcolax? *

female: 50 %
male: 50 %

What is the age of people who have Ankylosing spondylitis when taking Dulcolax? *

What are other drugs people take besides Dulcolax? *

What are other side effects people have besides Ankylosing spondylitis? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 13 people, 81.25%
Fatigue (feeling of tiredness): 12 people, 75.00%
Haematochezia (passage of stools containing blood): 12 people, 75.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 12 people, 75.00%
Joint Pain: 12 people, 75.00%
Pain: 12 people, 75.00%
Intervertebral Disc Degeneration (spinal disc degeneration): 11 people, 68.75%
Stress And Anxiety: 10 people, 62.50%
Osteoporosis (bones weak and more likely to break): 10 people, 62.50%
Exostosis (formation of new bone on the surface of a bone): 10 people, 62.50%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 56.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 37.50%
High Blood Cholesterol: 4 people, 25.00%
Uveitis (inflammation of the uvea): 3 people, 18.75%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 18.75%
Gastric Ulcer (stomach ulcer): 3 people, 18.75%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 18.75%
High Blood Pressure: 3 people, 18.75%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 18.75%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Dulcolax and have Ankylosing spondylitis?

- Check whether Ankylosing spondylitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dulcolax:

Dulcolax (12,897 reports)

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (748 drugs)

Browse all the conditions that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (1,048 conditions)

Related publications that referenced our studies

Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .
Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl (the active ingredients of Dulcolax) and Dulcolax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.