Dulcolax and Spinal compression fracture - a phase IV clinical study of FDA data

Summary:

Spinal compression fracture is reported as a side effect among people who take Dulcolax (bisacodyl), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Colace, and have Metastases to bone.

The phase IV clinical study analyzes which people have Spinal compression fracture when taking Dulcolax. It is created by eHealthMe based on reports of 12,769 people who have side effects when taking Dulcolax from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Spinal compression fracture?

Spinal compression fracture (fracture due to spinal compression on bone) is found to be associated with 1,089 drugs and 904 conditions by eHealthMe. Check the latest studies of Spinal compression fracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

12,769 people reported to have side effects when taking Dulcolax.
Among them, 43 people (0.34%) have Spinal compression fracture.

$Could Dulcolax cause Spinal compression fracture?$

Among these 43 people:

How long have people been on Dulcolax when they have Spinal compression fracture? *

What is the gender of people who have Spinal compression fracture when taking Dulcolax? *

female: 55.81 %
male: 44.19 %

What is the age of people who have Spinal compression fracture when taking Dulcolax? *

What are other drugs people take besides Dulcolax? *

What are other side effects people have besides Spinal compression fracture? *

Fall: 23 people, 53.49%
Back Pain: 21 people, 48.84%
Weakness: 19 people, 44.19%
Weight Decreased: 17 people, 39.53%
Stress And Anxiety: 17 people, 39.53%
Fever: 16 people, 37.21%
Pain: 16 people, 37.21%
Osteonecrosis Of Jaw (death of bone of jaw): 16 people, 37.21%
Dyspnea (difficult or laboured breathing): 14 people, 32.56%
Rashes (redness): 14 people, 32.56%

What are the existing conditions these people have? *

Stress And Anxiety: 10 people, 23.26%
Metastases To Bone (cancer spreads to bone): 10 people, 23.26%
Pain: 8 people, 18.60%
Multiple Myeloma (cancer of the plasma cells): 7 people, 16.28%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 7 people, 16.28%
Nausea (feeling of having an urge to vomit): 5 people, 11.63%
Osteoporosis (bones weak and more likely to break): 4 people, 9.30%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 6.98%
Parkinson's Disease: 3 people, 6.98%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

Do you take Dulcolax and have Spinal compression fracture?

- Check whether Spinal compression fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dulcolax:

Dulcolax (12,897 reports)

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal compression fracture:

Spinal compression fracture (1,089 drugs)

Browse all the conditions that are associated with Spinal compression fracture:

Spinal compression fracture (904 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl (the active ingredients of Dulcolax) and Dulcolax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.