Spravato and Pneumonia - a phase IV clinical study of FDA data

Summary:

Pneumonia is reported as a side effect among people who take Spravato (esketamine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Wellbutrin, and have Depression.

The phase IV clinical study analyzes which people have Pneumonia when taking Spravato. It is created by eHealthMe based on reports of 7,912 people who have side effects when taking Spravato from the FDA, and is updated regularly.

What is Spravato?

Spravato has active ingredients of esketamine hydrochloride. eHealthMe is studying from 7,920 Spravato users. Check the latest studies of Spravato.

What is Pneumonia?

Pneumonia is found to be associated with 3,353 drugs and 4,680 conditions by eHealthMe. Check the latest studies of Pneumonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

7,912 people reported to have side effects when taking Spravato.
Among them, 25 people (0.32%) have Pneumonia.

Among these 25 people:

How long have people been on Spravato when they have Pneumonia? *

What is the gender of people who have Pneumonia when taking Spravato? *

female: 64 %
male: 36 %

What is the age of people who have Pneumonia when taking Spravato? *

What are other drugs people take besides Spravato? *

What are other side effects people have besides Pneumonia? *

Dissociation: 5 people, 20.00%
Heart Attack: 3 people, 12.00%
Loss Of Consciousness: 2 people, 8.00%
Memory Loss: 2 people, 8.00%
Sedation: 2 people, 8.00%
Dizziness: 2 people, 8.00%
Nausea (feeling of having an urge to vomit): 2 people, 8.00%
Weight Increased: 1 person, 4.00%
Fall: 1 person, 4.00%
Hallucination, Visual (seeing things that aren't there): 1 person, 4.00%

What are the existing conditions these people have? *

Depression: 19 people, 76.00%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 5 people, 20.00%
Mood Swings (an extreme or rapid change in mood): 2 people, 8.00%
Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 2 people, 8.00%
Vitamin B12 Deficiency: 1 person, 4.00%
Suicidal Ideation: 1 person, 4.00%
Stress And Anxiety: 1 person, 4.00%
Rickets (softening of bones): 1 person, 4.00%
Pain: 1 person, 4.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Spravato and have Pneumonia?

- Check whether Pneumonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spravato:

Spravato (7,920 reports)

Pneumonia treatments and more:

Pneumonia (433,139 reports)

Browse all side effects of Spravato:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pneumonia:

Pneumonia (3,353 drugs)

Browse all the conditions that are associated with Pneumonia:

Pneumonia (4,680 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on esketamine hydrochloride (the active ingredients of Spravato) and Spravato (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.