Duphalac and Pain in extremity - a phase IV clinical study of FDA data

Summary:

Pain in extremity is reported as a side effect among people who take Duphalac (lactulose), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Calcium, and have Nausea.

The phase IV clinical study analyzes which people have Pain in extremity when taking Duphalac. It is created by eHealthMe based on reports of 5,136 people who have side effects when taking Duphalac from the FDA, and is updated regularly.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.

What is Pain in extremity?

Pain in extremity is found to be associated with 3,237 drugs and 4,292 conditions by eHealthMe. Check the latest studies of Pain in extremity.

On Jul, 11, 2026

5,136 people reported to have side effects when taking Duphalac.
Among them, 60 people (1.17%) have Pain in extremity.

Among these 60 people:

How long have people been on Duphalac when they have Pain in extremity? *

What is the gender of people who have Pain in extremity when taking Duphalac? *

female: 70 %
male: 30 %

What is the age of people who have Pain in extremity when taking Duphalac? *

What are other drugs people take besides Duphalac? *

Abstral: 12 people, 20.00%
Fulvestrant: 12 people, 20.00%
Dimenhydrinate: 12 people, 20.00%
Ondansetron: 12 people, 20.00%
Calcium: 12 people, 20.00%
Amlodipine: 11 people, 18.33%
Xanax: 11 people, 18.33%
Aldactone: 10 people, 16.67%
Hydrea: 10 people, 16.67%
Loperamide Hydrochloride: 10 people, 16.67%

What are other side effects people have besides Pain in extremity? *

Pain: 27 people, 45.00%
Fatigue (feeling of tiredness): 22 people, 36.67%
High Blood Pressure: 21 people, 35.00%
Gait Disturbance: 19 people, 31.67%
Muscle Spasms (muscle contraction): 18 people, 30.00%
Chills (felling of cold): 17 people, 28.33%
Diarrhea: 16 people, 26.67%
Joint Pain: 16 people, 26.67%
Weakness: 16 people, 26.67%
Oedema Peripheral (superficial swelling): 16 people, 26.67%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 17 people, 28.33%
Nausea And Vomiting: 15 people, 25.00%
Breast Cancer Metastatic: 12 people, 20.00%
Discomfort: 12 people, 20.00%
Diarrhea: 12 people, 20.00%
High Blood Pressure: 10 people, 16.67%
Ovarian Cancer (cancer of ovary): 10 people, 16.67%
Pain: 7 people, 11.67%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 6 people, 10.00%
Heart Disease: 6 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Duphalac and have Pain in extremity?

- Check whether Pain in extremity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duphalac:

Duphalac (5,152 reports)

Pain in extremity treatments and more:

Pain in extremity (376,792 reports)

Browse all side effects of Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain in extremity:

Pain in extremity (3,237 drugs)

Browse all the conditions that are associated with Pain in extremity:

Pain in extremity (4,292 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lactulose (the active ingredients of Duphalac) and Duphalac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.