Duphalac and Thrombophlebitis - a phase IV clinical study of FDA data

Summary:

Thrombophlebitis is reported as a side effect among people who take Duphalac (lactulose), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Abilify, and have Psychotic disorder.

The phase IV clinical study analyzes which people have Thrombophlebitis when taking Duphalac. It is created by eHealthMe based on reports of 5,136 people who have side effects when taking Duphalac from the FDA, and is updated regularly.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.

What is Thrombophlebitis?

Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot) is found to be associated with 936 drugs and 1,267 conditions by eHealthMe. Check the latest studies of Thrombophlebitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

5,136 people reported to have side effects when taking Duphalac.
Among them, 14 people (0.27%) have Thrombophlebitis.

Among these 14 people:

How long have people been on Duphalac when they have Thrombophlebitis? *

What is the gender of people who have Thrombophlebitis when taking Duphalac? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Thrombophlebitis when taking Duphalac? *

What are other drugs people take besides Duphalac? *

Zyprexa: 6 people, 42.86%
Eliquis: 6 people, 42.86%
Abilify: 6 people, 42.86%
Mucomyst: 4 people, 28.57%
Ivabradine Hydrochloride: 2 people, 14.29%
Lovenox: 2 people, 14.29%
Xarelto: 2 people, 14.29%
Dacarbazine: 2 people, 14.29%
Crestor: 2 people, 14.29%
Atarax: 2 people, 14.29%

What are other side effects people have besides Thrombophlebitis? *

Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 8 people, 57.14%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 5 people, 35.71%
Endometrial Cancer: 5 people, 35.71%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 28.57%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 14.29%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 14.29%
Cytolytic Hepatitis (dissolution or destruction of a liver cell): 2 people, 14.29%
General Physical Health Deterioration (weak health status): 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%
Leukopenia (less number of white blood cells in blood): 2 people, 14.29%

What are the existing conditions these people have? *

Psychotic Disorder: 6 people, 42.86%
Embolism Venous (embolus may pass into the arterial system): 4 people, 28.57%
Pain: 3 people, 21.43%
Stress And Anxiety: 3 people, 21.43%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 2 people, 14.29%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 14.29%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 14.29%
High Blood Pressure: 1 person, 7.14%
Dyspnea (difficult or laboured breathing): 1 person, 7.14%
Fungal Infection: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Duphalac and have Thrombophlebitis?

- Check whether Thrombophlebitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duphalac:

Duphalac (5,152 reports)

Thrombophlebitis treatments and more:

Thrombophlebitis (13,501 reports)

Browse all side effects of Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombophlebitis:

Thrombophlebitis (936 drugs)

Browse all the conditions that are associated with Thrombophlebitis:

Thrombophlebitis (1,267 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lactulose (the active ingredients of Duphalac) and Duphalac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.