Duragesic-100 and Sinus headache - a phase IV clinical study of FDA data

Summary:

Sinus headache is reported as a side effect among people who take Duragesic-100 (fentanyl), especially for people who are female, 50-59 old, also take Zometa, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Sinus headache when taking Duragesic-100. It is created by eHealthMe based on reports of 19,454 people who have side effects when taking Duragesic-100 from the FDA, and is updated regularly.

What is Duragesic-100?

Duragesic-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 19,509 Duragesic-100 users. Check the latest studies of Duragesic-100.

What is Sinus headache?

Sinus headache (headache caused by sinus infections) is found to be associated with 690 drugs and 791 conditions by eHealthMe. Check the latest studies of Sinus headache.

On Jul, 11, 2026

19,454 people reported to have side effects when taking Duragesic-100.
Among them, 29 people (0.15%) have Sinus headache.

Could Duragesic-100 cause Sinus headache?

Among these 29 people:

What is the gender of people who have Sinus headache when taking Duragesic-100? *

female: 72.41 %
male: 27.59 %

What is the age of people who have Sinus headache when taking Duragesic-100? *

What are other drugs people take besides Duragesic-100? *

What are other side effects people have besides Sinus headache? *

Insomnia (sleeplessness): 20 people, 68.97%
Dizziness: 15 people, 51.72%
Fall: 15 people, 51.72%
Stress And Anxiety: 15 people, 51.72%
Bone Disorder: 14 people, 48.28%
Pleural Effusion (water on the lungs): 14 people, 48.28%
Weakness: 13 people, 44.83%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 12 people, 41.38%
Metastases To Bone (cancer spreads to bone): 12 people, 41.38%
Rashes (redness): 12 people, 41.38%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 27.59%
Depression: 7 people, 24.14%
Breast Cancer: 3 people, 10.34%
Breakthrough Pain: 2 people, 6.90%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.45%
Nausea (feeling of having an urge to vomit): 1 person, 3.45%
Muscle Spasms (muscle contraction): 1 person, 3.45%
Menopausal Symptoms: 1 person, 3.45%
Indigestion: 1 person, 3.45%
Constipation: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Duragesic-100 and have Sinus headache?

- Check whether Sinus headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duragesic-100:

Duragesic-100 (19,509 reports)

Sinus headache treatments and more:

Sinus headache (9,129 reports)

Browse all side effects of Duragesic-100:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus headache:

Sinus headache (690 drugs)

Browse all the conditions that are associated with Sinus headache:

Sinus headache (791 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl (the active ingredients of Duragesic-100) and Duragesic-100 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.