Dyazide and Hypercalcaemia - a phase IV clinical study of FDA data

Summary:

Hypercalcaemia is reported as a side effect among people who take Dyazide (hydrochlorothiazide; triamterene), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Aredia, and have Metastases to bone.

The phase IV clinical study analyzes which people have Hypercalcaemia when taking Dyazide. It is created by eHealthMe based on reports of 11,105 people who have side effects when taking Dyazide from the FDA, and is updated regularly.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.

What is Hypercalcaemia?

Hypercalcaemia (elevated calcium (ca+) level in the blood) is found to be associated with 1,059 drugs and 1,017 conditions by eHealthMe. Check the latest studies of Hypercalcaemia.

On Aug, 02, 2026

11,105 people reported to have side effects when taking Dyazide.
Among them, 42 people (0.38%) have Hypercalcaemia.

Among these 42 people:

How long have people been on Dyazide when they have Hypercalcaemia? *

What is the gender of people who have Hypercalcaemia when taking Dyazide? *

female: 90 %
male: 10 %

What is the age of people who have Hypercalcaemia when taking Dyazide? *

What are other drugs people take besides Dyazide? *

What are other side effects people have besides Hypercalcaemia? *

Osteomyelitis (infection of bone): 23 people, 54.76%
Pain: 23 people, 54.76%
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 22 people, 52.38%
Stress And Anxiety: 22 people, 52.38%
Intervertebral Disc Degeneration (spinal disc degeneration): 22 people, 52.38%
Urinary Tract Infection: 22 people, 52.38%
Anaemia (lack of blood): 22 people, 52.38%
Osteonecrosis Of Jaw (death of bone of jaw): 21 people, 50.00%
Acute Kidney Failure: 20 people, 47.62%
Bone Disorder: 19 people, 45.24%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 10 people, 23.81%
Breast Cancer: 7 people, 16.67%
Senile Osteoporosis (weak bones with ageing): 5 people, 11.90%
Diabetes: 5 people, 11.90%
Osteoporosis (bones weak and more likely to break): 4 people, 9.52%
Pain: 3 people, 7.14%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 7.14%
Nausea (feeling of having an urge to vomit): 2 people, 4.76%
Stress And Anxiety: 2 people, 4.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Dyazide and have Hypercalcaemia?

- Check whether Hypercalcaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dyazide:

Dyazide (11,506 reports)

Hypercalcaemia treatments and more:

Hypercalcaemia (18,731 reports)

How severe was Hypercalcaemia and when was it recovered:

Hypercalcaemia in Dyazide

Expand to all the drugs that have ingredients of hydrochlorothiazide; triamterene:

Hypercalcaemia and drugs with ingredients of hydrochlorothiazide; triamterene (92 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dyazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercalcaemia:

Hypercalcaemia (1,059 drugs)

Browse all the conditions that are associated with Hypercalcaemia:

Hypercalcaemia (1,017 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; triamterene (the active ingredients of Dyazide) and Dyazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.