Effexor and Melanosis coli - a phase IV clinical study of FDA data

Summary:

Melanosis coli is reported as a side effect among people who take Effexor (venlafaxine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lisinopril, and have Osteoporosis.

The phase IV clinical study analyzes which people have Melanosis coli when taking Effexor. It is created by eHealthMe based on reports of 92,291 people who have side effects when taking Effexor from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,496 Effexor users. Check the latest studies of Effexor.

What is Melanosis coli?

Melanosis coli (a condition that can be caused from chronic laxative abuse) is found to be associated with 114 drugs and 157 conditions by eHealthMe. Check the latest studies of Melanosis coli.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

92,291 people reported to have side effects when taking Effexor.
Among them, 19 people (0.02%) have Melanosis coli.

Among these 19 people:

How long have people been on Effexor when they have Melanosis coli? *

What is the gender of people who have Melanosis coli when taking Effexor? *

female: 94.74 %
male: 5.26 %

What is the age of people who have Melanosis coli when taking Effexor? *

What are other drugs people take besides Effexor? *

What are other side effects people have besides Melanosis coli? *

Diarrhea: 18 people, 94.74%
Fall: 16 people, 84.21%
Abdominal Pain Lower: 16 people, 84.21%
Dry Eyes (lack of adequate tears): 16 people, 84.21%
Wound Infection Pseudomonas: 15 people, 78.95%
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein): 15 people, 78.95%
Joint Dislocation (a joint position is changed from normal position): 15 people, 78.95%
Itching: 15 people, 78.95%
Intertrigo (inflammation (rash) of the body folds (adjacent areas of skin)): 15 people, 78.95%
Weight Loss: 15 people, 78.95%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 15 people, 78.95%
Urinary Tract Infection: 1 person, 5.26%
Stomatitis (inflammation of mucous membrane of mouth): 1 person, 5.26%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 5.26%
Rashes (redness): 1 person, 5.26%
Mouth Ulcers: 1 person, 5.26%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 5.26%
Insomnia (sleeplessness): 1 person, 5.26%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.26%
Anaemia (lack of blood): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Effexor and have Melanosis coli?

- Check whether Melanosis coli is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Effexor:

Effexor (99,496 reports)

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Melanosis coli:

Melanosis coli (114 drugs)

Browse all the conditions that are associated with Melanosis coli:

Melanosis coli (157 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride (the active ingredients of Effexor) and Effexor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.