Eldepryl and Muscle rigidity - a phase IV clinical study of FDA data

Summary:

Muscle rigidity is reported as a side effect among people who take Eldepryl (selegiline hydrochloride), especially for people who are male, 60+ old, also take Sinemet,.

The phase IV clinical study analyzes which people have Muscle rigidity when taking Eldepryl. It is created by eHealthMe based on reports of 742 people who have side effects when taking Eldepryl from the FDA, and is updated regularly.

What is Eldepryl?

Eldepryl has active ingredients of selegiline hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 752 Eldepryl users. Check the latest studies of Eldepryl.

What is Muscle rigidity?

Muscle rigidity (muscle stiffness) is found to be associated with 787 drugs and 1,035 conditions by eHealthMe. Check the latest studies of Muscle rigidity.



On Jul, 08, 2026

742 people reported to have side effects when taking Eldepryl.
Among them, 29 people (3.91%) have Muscle rigidity.

Could Eldepryl cause Muscle rigidity?

Among these 29 people:

What is the gender of people who have Muscle rigidity when taking Eldepryl? *

  • female: 41.38 %
  • male: 58.62 %

What is the age of people who have Muscle rigidity when taking Eldepryl? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 23.08 %
  • 60+: 76.92 %

What are other drugs people take besides Eldepryl? *

  1. Sinemet: 14 people, 48.28%
  2. Tasmar: 10 people, 34.48%
  3. Permax: 9 people, 31.03%
  4. Nubain: 7 people, 24.14%
  5. Mirapex: 6 people, 20.69%
  6. Prilosec: 3 people, 10.34%
  7. Fosamax: 3 people, 10.34%
  8. Norvasc: 3 people, 10.34%
  9. Paxil: 3 people, 10.34%
  10. Symmetrel: 3 people, 10.34%

What are other side effects people have besides Muscle rigidity? *

  1. Confusion: 11 people, 37.93%
  2. Fever: 10 people, 34.48%
  3. Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 10 people, 34.48%
  4. Swallowing Difficulty: 5 people, 17.24%
  5. Difficulty In Walking: 5 people, 17.24%
  6. Blood Creatine Phosphokinase Increased: 5 people, 17.24%
  7. Fall: 4 people, 13.79%
  8. Movement - Uncontrolled Or Slow: 4 people, 13.79%
  9. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 4 people, 13.79%
  10. Nausea (feeling of having an urge to vomit): 4 people, 13.79%

* Approximation only. Some reports may have incomplete information.

Do you take Eldepryl and have Muscle rigidity?

- Check whether Muscle rigidity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eldepryl:

Muscle rigidity treatments and more:

How severe was Muscle rigidity and when was it recovered:

Expand to all the drugs that have ingredients of selegiline hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eldepryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle rigidity:

Browse all the conditions that are associated with Muscle rigidity:


How the study uses the data?

The study uses data from the FDA. It is based on selegiline hydrochloride (the active ingredients of Eldepryl) and Eldepryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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