Eliquis and Guillain barre syndrome - a phase IV clinical study of FDA data

Summary:

Guillain barre syndrome is reported as a side effect among people who take Eliquis (apixaban), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Folic Acid, and have High blood pressure.

The phase IV clinical study analyzes which people have Guillain barre syndrome when taking Eliquis. It is created by eHealthMe based on reports of 189,425 people who have side effects when taking Eliquis from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,844 Eliquis users. Check the latest studies of Eliquis.

What is Guillain barre syndrome?

Guillain barre syndrome (the body's immune system attacks its peripheral nervous system) is found to be associated with 471 drugs and 1,205 conditions by eHealthMe. Check the latest studies of Guillain barre syndrome.

On Mar, 25, 2026

189,425 people reported to have side effects when taking Eliquis.
Among them, 18 people (0.01%) have Guillain barre syndrome.

Could Eliquis cause Guillain barre syndrome?

Among these 18 people:

How long have people been on Eliquis when they have Guillain barre syndrome? *

What is the gender of people who have Guillain barre syndrome when taking Eliquis? *

female: 23.53 %
male: 76.47 %

What is the age of people who have Guillain barre syndrome when taking Eliquis? *

What are other drugs people take besides Eliquis? *

What are other side effects people have besides Guillain barre syndrome? *

Axonal Neuropathy (dysfunction of axon nerves): 6 people, 33.33%
Weight Decreased: 4 people, 22.22%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 22.22%
Overdose: 3 people, 16.67%
Ageusia (loss of taste functions of the tongue): 2 people, 11.11%
Balance Disorder: 2 people, 11.11%
Diarrhea: 2 people, 11.11%
Eye Irritation: 2 people, 11.11%
Hypoaesthesia (reduced sense of touch or sensation): 2 people, 11.11%
Immune System Disorder: 2 people, 11.11%

What are the existing conditions these people have? *

Iron Deficiency Anaemia: 6 people, 33.33%
Folate Deficiency (lack of folic acid): 6 people, 33.33%
High Blood Pressure: 6 people, 33.33%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 16.67%
Axonal Neuropathy (dysfunction of axon nerves): 3 people, 16.67%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 11.11%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 5.56%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Eliquis and have Guillain barre syndrome?

- Check whether Guillain barre syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eliquis:

Eliquis (191,844 reports)

Browse all side effects of Eliquis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Guillain barre syndrome:

Guillain barre syndrome (471 drugs)

Browse all the conditions that are associated with Guillain barre syndrome:

Guillain barre syndrome (1,205 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apixaban (the active ingredients of Eliquis) and Eliquis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.