Eliquis and Tenderness - a phase IV clinical study of FDA data

Summary:

Tenderness is reported as a side effect among people who take Eliquis (apixaban), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Tenderness when taking Eliquis. It is created by eHealthMe based on reports of 189,425 people who have side effects when taking Eliquis from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,861 Eliquis users. Check the latest studies of Eliquis.

What is Tenderness?

Tenderness (pain or discomfort when an affected area is touched) is found to be associated with 1,049 drugs and 1,014 conditions by eHealthMe. Check the latest studies of Tenderness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

189,425 people reported to have side effects when taking Eliquis.
Among them, 80 people (0.04%) have Tenderness.

Among these 80 people:

How long have people been on Eliquis when they have Tenderness? *

What is the gender of people who have Tenderness when taking Eliquis? *

female: 75 %
male: 25 %

What is the age of people who have Tenderness when taking Eliquis? *

What are other drugs people take besides Eliquis? *

What are other side effects people have besides Tenderness? *

Pain: 31 people, 38.75%
Joint Pain: 27 people, 33.75%
Pain In Extremity: 26 people, 32.50%
Fatigue (feeling of tiredness): 23 people, 28.75%
Peripheral Swelling: 22 people, 27.50%
Nausea (feeling of having an urge to vomit): 20 people, 25.00%
Headache (pain in head): 20 people, 25.00%
Rashes (redness): 19 people, 23.75%
Head Injury: 18 people, 22.50%
Diarrhea: 16 people, 20.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 12.50%
Neuroendocrine Tumor: 6 people, 7.50%
Carcinoid Tumor: 6 people, 7.50%
Immunodeficiency Common Variable: 5 people, 6.25%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 6.25%
Multiple Myeloma (cancer of the plasma cells): 5 people, 6.25%
Pain: 5 people, 6.25%
Immunodeficiency: 4 people, 5.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 3.75%
Urticaria Chronic (long lasting rash of round, red welts on the skin that itch intensely): 2 people, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Eliquis and have Tenderness?

- Check whether Tenderness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eliquis:

Eliquis (191,861 reports)

Tenderness treatments and more:

Tenderness (13,319 reports)

Browse all side effects of Eliquis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tenderness:

Tenderness (1,049 drugs)

Browse all the conditions that are associated with Tenderness:

Tenderness (1,014 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apixaban (the active ingredients of Eliquis) and Eliquis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.