Emend and Purpura - a phase IV clinical study of FDA data

Summary:

Purpura is reported as a side effect among people who take Emend (aprepitant), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Solu-Medrol, and have Colon cancer.

The phase IV clinical study analyzes which people have Purpura when taking Emend. It is created by eHealthMe based on reports of 13,708 people who have side effects when taking Emend from the FDA, and is updated regularly.

What is Emend?

Emend has active ingredients of aprepitant. It is often used in nausea. eHealthMe is studying from 13,741 Emend users. Check the latest studies of Emend.

What is Purpura?

Purpura (purplish discoloration of the skin) is found to be associated with 941 drugs and 1,515 conditions by eHealthMe. Check the latest studies of Purpura.

On Jul, 14, 2026

13,708 people reported to have side effects when taking Emend.
Among them, 12 people (0.09%) have Purpura.

Among these 12 people:

How long have people been on Emend when they have Purpura? *

What is the gender of people who have Purpura when taking Emend? *

female: 16.67 %
male: 83.33 %

What is the age of people who have Purpura when taking Emend? *

What are other drugs people take besides Emend? *

Solu-Medrol: 4 people, 33.33%
Zofran: 3 people, 25.00%
Neulasta: 3 people, 25.00%
Bactrim: 3 people, 25.00%
Atarax: 3 people, 25.00%
Propranolol Hydrochloride: 2 people, 16.67%
Metformin: 2 people, 16.67%
Warfarin Sodium: 1 person, 8.33%
Vectibix: 1 person, 8.33%
Tarceva: 1 person, 8.33%

What are other side effects people have besides Purpura? *

Thrombocytopenia (decrease of platelets in blood): 7 people, 58.33%
Fever: 6 people, 50.00%
Bone Marrow Failure: 6 people, 50.00%
Nosebleed (bleeding from nose): 4 people, 33.33%
Drug Ineffective: 3 people, 25.00%
Mucosal Inflammation (infection of mucous membrane): 3 people, 25.00%
Purpura Fulminans (destructive infections that involve both skin and soft tissues): 2 people, 16.67%
Consciousness - Decreased: 2 people, 16.67%
Oedema Peripheral (superficial swelling): 2 people, 16.67%
Septic Shock (shock due to blood infection): 2 people, 16.67%

What are the existing conditions these people have? *

Rectal Cancer (cancer of rectum): 1 person, 8.33%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 8.33%
Neoplasm Malignant (cancer tumour): 1 person, 8.33%
Metastases To Lung (cancer spreads to lung): 1 person, 8.33%
Hodgkin's Lymphoma (cancer originating from white blood cells): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Haematotoxicity (toxins that destroy red blood cells): 1 person, 8.33%
Cough: 1 person, 8.33%
Colon Cancer: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Emend and have Purpura?

- Check whether Purpura is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Emend:

Emend (13,741 reports)

Purpura treatments and more:

Purpura (10,762 reports)

Browse all side effects of Emend:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Purpura:

Purpura (941 drugs)

Browse all the conditions that are associated with Purpura:

Purpura (1,515 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant (the active ingredients of Emend) and Emend (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.