Bentyl and Estraderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bentyl (dicyclomine hydrochloride) and Estraderm (estradiol). Common drug interactions include chest pain among females.

The phase IV clinical study analyzes what interactions people have when they take Bentyl and Estraderm. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.

What is Estraderm?

Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.

On Jul, 17, 2026

20 people who take Bentyl and Estraderm together, and have interactions are studied.

What are the common drug interactions of Bentyl and Estraderm, by gender? *:

female:

Chest pain
Diarrhoea
Nausea (feeling of having an urge to vomit)
Pancreatitis chronic (chronic inflammation of pancreas)
Vomiting
Weight decreased
Cough
Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Irritability

male:

n/a

What are the common drug interactions of Bentyl and Estraderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Insomnia (sleeplessness)
Intestinal obstruction
Irritability
Klebsiella infection
Nervousness
Oral pain
Pain
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Chills (felling of cold)
Culture urine positive

50-59:

Hypotension (abnormally low blood pressure)
Intervertebral disc protrusion (spinal disc protrusion)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
Anxiety
Depressed mood
Diarrhoea
Fear
Hypokalaemia (low potassium)
Joint dislocation (a joint position is changed from normal position)

60+:

Abdominal pain upper
Arthralgia (joint pain)
Chest pain
Diarrhoea
Headache (pain in head)
Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Urinary tract infection
Chronic kidney disease

What are the existing conditions these people have? *

Pain: 7 people, 35.00%
Joint Pain: 2 people, 10.00%
Headache (pain in head): 2 people, 10.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 10.00%
Muscle Spasms (muscle contraction): 1 person, 5.00%
Inflammation: 1 person, 5.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.00%
Hot Flush (sudden feelings of heat): 1 person, 5.00%
High Blood Pressure: 1 person, 5.00%
General Physical Health Deterioration (weak health status): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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