Emla and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Emla (lidocaine; prilocaine), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zofran, and have Breast cancer female.

The phase IV clinical study analyzes which people have Joint swelling when taking Emla. It is created by eHealthMe based on reports of 5,268 people who have side effects when taking Emla from the FDA, and is updated regularly.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

What is Joint swelling?

Joint swelling is found to be associated with 2,122 drugs and 2,937 conditions by eHealthMe. Check the latest studies of Joint swelling.

On Aug, 08, 2026

5,268 people reported to have side effects when taking Emla.
Among them, 31 people (0.59%) have Joint swelling.

Among these 31 people:

How long have people been on Emla when they have Joint swelling? *

What is the gender of people who have Joint swelling when taking Emla? *

female: 67.86 %
male: 32.14 %

What is the age of people who have Joint swelling when taking Emla? *

What are other drugs people take besides Emla? *

What are other side effects people have besides Joint swelling? *

Joint Pain: 24 people, 77.42%
Weakness: 15 people, 48.39%
Headache (pain in head): 15 people, 48.39%
Abdominal Pain: 14 people, 45.16%
Fatigue (feeling of tiredness): 14 people, 45.16%
Nausea (feeling of having an urge to vomit): 14 people, 45.16%
Pain: 13 people, 41.94%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 13 people, 41.94%
Lymphoedema (localized fluid retention and tissue swelling): 13 people, 41.94%
Malaise (a feeling of general discomfort or uneasiness): 13 people, 41.94%

What are the existing conditions these people have? *

Breast Cancer Female: 9 people, 29.03%
Metastases To Bone (cancer spreads to bone): 8 people, 25.81%
Multiple Myeloma (cancer of the plasma cells): 6 people, 19.35%
Vision Blurred: 3 people, 9.68%
Night Sweats (sweating in night): 3 people, 9.68%
Balance Disorder: 3 people, 9.68%
Breast Cancer: 3 people, 9.68%
Diplopia (double vision): 3 people, 9.68%
Eye Pain: 3 people, 9.68%
Fall: 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Emla and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Emla:

Emla (5,276 reports)

Joint swelling treatments and more:

Joint swelling (143,797 reports)

Browse all side effects of Emla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Joint swelling (2,122 drugs)

Browse all the conditions that are associated with Joint swelling:

Joint swelling (2,937 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lidocaine; prilocaine (the active ingredients of Emla) and Emla (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.