Emsam and Agitation aggravated - a phase IV clinical study of FDA data

Summary:

Agitation aggravated is reported as a side effect among people who take Emsam (selegiline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Klonopin, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Agitation aggravated when taking Emsam. It is created by eHealthMe based on reports of 1,646 people who have side effects when taking Emsam from the FDA, and is updated regularly.

What is Emsam?

Emsam has active ingredients of selegiline. It is often used in depression. eHealthMe is studying from 1,875 Emsam users. Check the latest studies of Emsam.

What is Agitation aggravated?

Agitation aggravated (clinical depression in which the person exhibits irritability and restlessness) is found to be associated with 2,022 drugs and 914 conditions by eHealthMe. Check the latest studies of Agitation aggravated.

On Jul, 13, 2026

1,646 people reported to have side effects when taking Emsam.
Among them, 32 people (1.94%) have Agitation aggravated.

Among these 32 people:

How long have people been on Emsam when they have Agitation aggravated? *

What is the gender of people who have Agitation aggravated when taking Emsam? *

female: 70.97 %
male: 29.03 %

What is the age of people who have Agitation aggravated when taking Emsam? *

What are other drugs people take besides Emsam? *

What are other side effects people have besides Agitation aggravated? *

Stress And Anxiety: 10 people, 31.25%
Insomnia (sleeplessness): 6 people, 18.75%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 15.62%
Irritability: 5 people, 15.62%
Nervousness: 4 people, 12.50%
Anger: 4 people, 12.50%
Fatigue (feeling of tiredness): 3 people, 9.38%
Dizziness: 3 people, 9.38%
Nausea (feeling of having an urge to vomit): 3 people, 9.38%
Sleep Disorder: 3 people, 9.38%

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 18.75%
Panic Disorder: 2 people, 6.25%
Weakness: 1 person, 3.12%
Thyroid Diseases: 1 person, 3.12%
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 1 person, 3.12%
Pain: 1 person, 3.12%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 3.12%
Insomnia (sleeplessness): 1 person, 3.12%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 3.12%
Bipolar Disorder (mood disorder): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Emsam and have Agitation aggravated?

- Check whether Agitation aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Emsam:

Emsam (1,875 reports)

Browse all side effects of Emsam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Agitation aggravated:

Agitation aggravated (2,022 drugs)

Browse all the conditions that are associated with Agitation aggravated:

Agitation aggravated (914 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on selegiline (the active ingredients of Emsam) and Emsam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.