Enbrel and Bicytopenia - a phase IV clinical study of FDA data
Summary:
Bicytopenia is reported as a side effect among people who take Enbrel (etanercept), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Sulfasalazine, and have Psoriatic arthropathy.
The phase IV clinical study analyzes which people have Bicytopenia when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.
What is Enbrel?
Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.
What is Bicytopenia?
Bicytopenia (two parameters from the full blood count are low, the term bicytopenia can be used) is found to be associated with 226 drugs and 320 conditions by eHealthMe. Check the latest studies of Bicytopenia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
662,905 people reported to have side effects when taking Enbrel.
Among them, 24 people (0.0%) have Bicytopenia.

Among these 24 people:
How long have people been on Enbrel when they have Bicytopenia? *
- < 1 month: 0.0 %
- 1 - 6 months: 25 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 75 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Bicytopenia when taking Enbrel? *
- female: 70.83 %
- male: 29.17 %
What is the age of people who have Bicytopenia when taking Enbrel? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 4.17 %
- 20-29: 0.0 %
- 30-39: 12.5 %
- 40-49: 4.17 %
- 50-59: 4.17 %
- 60+: 75.0 %
What are other drugs people take besides Enbrel? *
- Methotrexate: 14 people, 58.33%
- Actemra: 14 people, 58.33%
- Sulfasalazine: 14 people, 58.33%
- Prednisone: 13 people, 54.17%
- Zoledronic Acid: 12 people, 50.00%
- Botox: 12 people, 50.00%
- Xeljanz: 12 people, 50.00%
- Tylenol: 12 people, 50.00%
- Orencia: 12 people, 50.00%
- Synthroid: 12 people, 50.00%
What are other side effects people have besides Bicytopenia? *
- Fatigue (feeling of tiredness): 13 people, 54.17%
- Joint Pain: 13 people, 54.17%
- Lung Disorder (lung disease): 12 people, 50.00%
- Swallowing Difficulty: 12 people, 50.00%
- Pneumonia: 12 people, 50.00%
- Bronchial Wall Thickening: 12 people, 50.00%
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 12 people, 50.00%
- Calcification Of Muscle (calcium accumulation in muscle): 12 people, 50.00%
- Osteoporosis (bones weak and more likely to break): 12 people, 50.00%
- Felty's Syndrome (a combination of rheumatoid arthritis, an enlarged spleen, an abnormally low white blood count): 12 people, 50.00%
What are the existing conditions these people have? *
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 12.50%
- The Flu (the flu is caused by an influenza virus): 1 person, 4.17%
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe): 1 person, 4.17%
- Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 1 person, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Enbrel and have Bicytopenia?
- Check whether Bicytopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Enbrel:
- Enbrel (664,678 reports)
Bicytopenia treatments and more:
- Bicytopenia (1,849 reports)
How severe was Bicytopenia and when was it recovered:
Expand to all the drugs that have ingredients of etanercept:
- Bicytopenia and drugs with ingredients of etanercept (26 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Enbrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Bicytopenia:
- Bicytopenia (226 drugs)
Browse all the conditions that are associated with Bicytopenia:
- Bicytopenia (320 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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