Enbrel and Chagas disease - a phase IV clinical study of FDA data
Summary:
Chagas disease is reported as a side effect among people who take Enbrel (etanercept), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Folic Acid, and have Angiopathy.
The phase IV clinical study analyzes which people have Chagas disease when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.
What is Enbrel?
Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.
What is Chagas disease?
Chagas disease (a parasite disease an insect vector, the blood-sucking ""kissing bugs) is found to be associated with 19 drugs and 110 conditions by eHealthMe. Check the latest studies of Chagas disease.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
662,905 people reported to have side effects when taking Enbrel.
Among them, 13 people (0.0%) have Chagas disease.

Among these 13 people:
How long have people been on Enbrel when they have Chagas disease? *
- < 1 month: 0.0 %
- 1 - 6 months: 20 %
- 6 - 12 months: 40 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 40 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Chagas disease when taking Enbrel? *
- female: 76.92 %
- male: 23.08 %
What is the age of people who have Chagas disease when taking Enbrel? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 8.33 %
- 50-59: 58.33 %
- 60+: 33.33 %
What are other drugs people take besides Enbrel? *
- Methotrexate: 3 people, 23.08%
- Folic Acid: 3 people, 23.08%
- Losartan: 2 people, 15.38%
- Sulfasalazine: 1 person, 7.69%
- Leflunomide: 1 person, 7.69%
- Hydrea: 1 person, 7.69%
- Furosemide: 1 person, 7.69%
- Asa: 1 person, 7.69%
- Arava: 1 person, 7.69%
- Amlodipine: 1 person, 7.69%
What are other side effects people have besides Chagas disease? *
- High Blood Pressure: 4 people, 30.77%
- Pneumonia: 3 people, 23.08%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 7.69%
- Cardiac Arrest: 1 person, 7.69%
- Chest Pain: 1 person, 7.69%
- Consciousness - Decreased: 1 person, 7.69%
- Decreased Immune Responsiveness: 1 person, 7.69%
- Depression: 1 person, 7.69%
- Gastrointestinal Infection (infection of stomach and intestine): 1 person, 7.69%
- Drug Effect Decreased: 1 person, 7.69%
What are the existing conditions these people have? *
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.69%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 7.69%
- High Blood Pressure: 1 person, 7.69%
- High Blood Cholesterol: 1 person, 7.69%
- Gastritis (inflammation of stomach): 1 person, 7.69%
- Angiopathy (generic term for a disease of the blood vessels): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Enbrel and have Chagas disease?
- Check whether Chagas disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Enbrel:
- Enbrel (664,678 reports)
Chagas disease treatments and more:
- Chagas disease (327 reports)
How severe was Chagas disease and when was it recovered:
Expand to all the drugs that have ingredients of etanercept:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Enbrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Chagas disease:
- Chagas disease (19 drugs)
Browse all the conditions that are associated with Chagas disease:
- Chagas disease (110 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Kadcyla cause Muscle Weakness Aggravated? - a second ago
- Could Ibrance cause Cardiac Murmur? - 3 seconds ago
- Could Forteo cause Blood Pressure Immeasurable? - 10 seconds ago
- Could Verapamil Hcl cause Respiratory Acidosis? - 14 seconds ago
- Could Zestril cause Intestinal Obstruction? - 18 seconds ago
- Could Olopatadine Hydrochloride cause Pain? - 25 seconds ago
- Could Nexium cause Allergy To Animal? - 26 seconds ago
- Could Darunavir cause Bone Density Decreased? - 26 seconds ago
- Could Iodine cause Hypoaesthesia? - 32 seconds ago
- Could Zometa cause Radicular Cyst? - 33 seconds ago